Association between social frailty as well as early physical dysfunction and exercise intolerance among older patients receiving hemodialysis
Association between social frailty as well as early physical dysfunction and exercise intolerance among older patients receiving hemodialysis
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接受血液透析的老年患者社交脆弱以及早期身体功能障碍和运动不耐受之间的关联
DOI：
10.1111/ggi.14223
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发表时间：
2021
影响因子：
3.3
通讯作者：
Uehata Akimi
中科院分区：
文献类型：
--
作者：
Usui Naoto;Yokoyama Minori;Nakata Junichiro;Suzuki Yusuke;Tsubaki Atsuhiro;Kojima Sho;Inatsu Akihito;Hisadome Hideki;Uehata Akimi
背景近年来，社会脆弱日益被认为是与包括身体残疾和死亡在内的不良健康结果相关的一个因素。然而，还没有关于这一因素在血液透析患者中的重要性的研究。因此，我们调查了这组患者的社会脆弱与早期身体功能障碍之间的关系。接受血液透析的老年患者是前瞻性研究对象。此外，根据先前研究的定义，对参与者进行了社会脆弱性评估，包括身体功能、最大摄氧量(峰值VO2)、二氧化碳通气量(VE/VCO2)斜率和心率储备。结果对158名调查对象的调查资料进行了统计分析。社会脆弱的患病率为59.5%。在非身体虚弱组中，社交脆弱与步速下降(P= 0.007)、腿力下降(P= 0.040)和最大摄氧量(P= 0.023)独立相关，但与握力无关(P= 0.36)。在身体虚弱组中，社交脆弱与身体机能之间没有关联。此外，在没有身体和社会脆弱的患者中，身体功能维持在高于可接受的阈值水平，而VO2峰值(14.1 ± 3.3min/kg/ )、VE/VCO2斜率(32.3 ± 5.5)和心率储备(50.8% ± 21.7%)显著受损。结论血液透析患者在早期可出现社会脆弱和运动耐受并伴有心功能障碍，这可能是随后功能障碍的原因之一。
BackgroundRecently, social frailty has been increasingly recognized as a factor associated with adverse health outcomes, including physical disability and mortality. However, there are no studies about the importance of this factor among hemodialysis patients. Therefore, we investigated the relationship between social frailty and early physical dysfunction in this group of patients.MethodsThis was a two‐center cross‐sectional study. Older patients receiving hemodialysis were prospectively enrolled. Moreover, participants were evaluated for social frailty based on the definition of previous study and for physical function, peak oxygen uptake (peak VO2), ventilatory equivalent for carbon dioxide (VE/VCO2) slope and heart rate reserve. Then, they were divided into two groups based on the presence of physical frailty.ResultsData collected from 158 individuals were statistically analyzed. The prevalence rate of social frailty was 59.5%. In the non‐physical frailty group, social frailty was found to be independently associated with reduced gait speed (P= 0.007), leg strength (P= 0.040) and peak VO2(P= 0.023), but not with hand grip strength (P= 0.36). In the physical frailty group, there was no association between social frailty and physical function. Moreover, in patients without physical and social frailty, physical function was maintained at above accepted threshold levels, whereas peak VO2(14.1 ± 3.3 mL/kg/min), VE/VCO2slope (32.3 ± 5.5) and heart rate reserve (50.8% ± 21.7%) were substantially impaired.ConclusionsPatients receiving hemodialysis can present with social frailty and exercise intolerance with cardiac dysfunction in the early phase, which may contribute to subsequent dysfunction.Geriatr Gerontol Int 2021; 21: 664–669.
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%20增量%20预后%20值%20of%20百分比%20of%20心脏%20率%20储备%20实现%20超过%20心肌%20灌注%20单光子%20发射%20计算%20断层扫描%20in%20%20预测%20%20心脏%20死亡%
影响因子：
24
作者：
B. Azarbal;S. Hayes;H. Lewin;R. Hachamovitch;I. Cohen;D. Berman
通讯作者：
D. Berman
影响因子：
3.2
作者：
Panaye, Marine;Kolko-Labadens, Anne;Fouque, Denis
通讯作者：
Fouque, Denis
CHS 快离子激发不稳定过程中内部结构演化的观察
DOI：
--
发表时间：
2007
期刊：
影响因子：
--
作者：
大島慎介;藤澤彰英;清水昭博;中野治久;CHS グループ
通讯作者：
CHS グループ
社区生活老年人不同类型居家的预后。
DOI：
--
发表时间：
2005
期刊：
Japanese Journal of Public Health 52
影响因子：
--
作者：
Shinkai S;Fujita K;Fujiwara Y;et. al.
通讯作者：
et. al.
社区生活老年人中不同类型居家行为发生的预测因素。
DOI：
--
发表时间：
2005
期刊：
Japanese Journal of Public Health 52
影响因子：
--
作者：
Shinkai S;Fujita K;Fujiwara Y;et. al.
通讯作者：
et. al.