Secondary flow velocity patterns in a pulmonary artery model with varying degrees of valvular pulmonic stenosis: pulsatile in vitro studies.
Secondary flow velocity patterns in a pulmonary artery model with varying degrees of valvular pulmonic stenosis: pulsatile in vitro studies.
复制标题
具有不同程度的瓣膜性肺动脉狭窄的肺动脉模型中的二次流速模式：脉动体外研究。
DOI：
10.1115/1.2891131
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发表时间：
1990
期刊：
影响因子：
--
通讯作者：
Yoganathan,AP
中科院分区：
文献类型：
--
作者：
Sung,HW;Yoganathan,AP
本研究的目的是详细描述具有不同程度肺动脉瓣狭窄的人（成人）肺动脉体外模型中的二次流速模式。采用二维激光多普勒风速仪（LDA）系统绘制肺动脉模型主支（MPA）、左支（LPA）和右支（RPA）的流场。本研究在格鲁吉亚理工学院右心脉冲复制器系统中进行。在每个子分支中观察到一对反向旋转的二次流，其中流体沿着侧壁向外移动，然后朝向血管中心向内盘旋。对于“正常”阀门的情况，两个反向旋转的二次流关于中心线对称。RPA中二次流的强度比LPA中强得多。然而，随着肺动脉瓣变得更加狭窄，LPA和RPA中的两个反向旋转二次流不再对称。此外，随着瓣膜狭窄程度的增加，两个子支的二次血流强度也增加。然而，《地方行政法》的增加幅度大于《区域行政法》。这项研究表明了从三维角度分析复杂生物流动的重要性。
The objective of this study was to characterize in detail the secondary flow velocity patterns in an in vitro model of a human (adult) pulmonary artery with varying degrees of valvular pulmonic stenosis. A two-dimensional laser Doppler anemometer (LDA) system was used to map the flow fields in the main (MPA), left (LPA), and right (RPA) branches of the pulmonary artery model. The study was conducted in the Georgia Tech right heart pulse duplicator system. A pair of counter-rotating secondary flows were observed in each daughter branch in which the fluid moved outwardly along the side walls and then circled back inwardly toward the center of the vessel. For the case of the “normal” valve, the two counter-rotating secondary flows were symmetric about the centerline. The strength of secondary flows in the RPA was much stronger than in the LPA. However, as the pulmonic valve became more stenotic, the two counter-rotating secondary flows in both the LPA and RPA were no longer symmetric. In addition, the strength of secondary flows in both daughter branches increased with increasing degree of valvular stenosis. The increment in the LPA was, however, greater than in the RPA. The study demonstrates the importance of analyzing complex biological flows from a three-dimensional viewpoint.