Optimal search strategies for retrieving scientifically strong studies of diagnosis from Medline: analytical survey

Optimal search strategies for retrieving scientifically strong studies of diagnosis from Medline: analytical survey
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DOI:
10.1136/bmj.38068.557998.ee
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发表时间:
2004-05-01
影响因子:
105.7
通讯作者:
Wilczynski, NL
Wilczynski, NL
中科院分区:
医学1区
文献类型:
--
作者:
Haynes, RB;Wilczynski, NL

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目的通过对2000年出版的161种期刊(490 028篇)的手工检索(金标准)的比较,确定最佳的检索策略,以检索关于健康障碍诊断的可靠的临床研究。研究对象为2000年的170种期刊,其中161种被Medline收录。主要结果通过与手工检索所有文献(49028篇)比较,确定17287种组合中4862个唯一术语的敏感性、特异性、精确度和准确性。搜索词的组合达到了98.6%的峰值灵敏度,特异度为74.3%。与最佳单项相比,最佳多项对声音研究的敏感度提高了6.8%(绝对增加),同时当敏感度最大化时,特异度也增加了(绝对增加6.0%)。当术语组合在一起以最大限度地具体化时,单个术语,Speciciatiy.tw。(98.4%),表现优于各项组合。除了一种略高的敏感性(99.3%vs98.6%)和较低的特异性(54.7%vs74.3%)外,本文报道的新的经验性搜索策略优于其他有效的搜索策略。结论Medline新的经验性搜索策略可以优化报告高质量临床诊断研究的文章的检索。
Objective To develop optimal search strategies in Medline for retrieving sound clinical studies on the diagnosis of health disorders.Design Analytical survey.Setting Medline, 2000.Participants 170 journals for 2000 of which 161 were indexed in Medline.Main outcome measures The sensitivity, specificity, precision ("positive predictive value"), and accuracy of 4862 unique terms in 17 287 combinations were determined by comparison with a hand search of all articles (the "gold standard") in 161 journals published during 2000 (49 028 articles).Results Only 147 (18.9%) of 778 articles about diagnostic tests met basic criteria for scientific merit. Combinations of search terms reached peak sensitivities of 98.6% at a specificity of 74.3%. Compared with best single terms, best multiple terms increased sensitivity for sound studies by 6.8% (absolute increase), while also increasing specificity (absolute increase 6.0%) when sensitivity was maximised. When terms were combined to maximise specificity, the single term, specificity.tw. (98.4%), outperformed combinations of terms. The strategies newly reported in this paper outperformed other validated search strategies except for one strategy that had slightly higher sensitivity (99.3% v 98.6%) but lower specificity (54.7% v 74.3%).Conclusion New empirical search strategies in Medline can optimise retrieval of articles reporting high quality clinical studies of diagnosis.