A developmental study of the effect of temporal order on the ERPs elicited by novel environmental sounds
A developmental study of the effect of temporal order on the ERPs elicited by novel environmental sounds
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DOI：
10.1016/s0013-4694(97)96053-3
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发表时间：
1997-08-01
期刊：
影响因子：
--
通讯作者：
Friedman, D
中科院分区：
文献类型：
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作者：
Cycowicz, YM;Friedman, D
事件相关脑电位（ERP）记录了16名受试者在以下年龄组，5-7，9-11，14-16，20-28岁。受试者执行一项新奇古怪的任务，其中频繁的标准音调（80%的概率）与受试者响应的不频繁音调（10%）混合，沿着48种独特的环境声音（10%）。分析集中在时间顺序（无论是在块内的序列顺序或块号）与年龄组的相互作用对事件相关电位的影响的新的声音。分析了两个ERP成分的幅度和头皮分布，“新奇P3”被认为反映了定向反应的各个方面，而P3（2）可能与P3 b同义。有证据表明，新奇P3的头皮分布的正面取决于前额叶皮层的完整性。时间顺序产生的系统（主要是线性）减少新奇P3振幅，更大的正面比后电极网站。P3（2）没有表现出时间顺序的一致影响。这两种现象在所有四个年龄组中都非常相似。它的结论是，新奇的反应是相似的，在很宽的年龄范围内，涉及到一个神经回路与额叶和后部元素。(C)1997 Elsevier Science爱尔兰有限公司
Event-related brain potentials (ERPs) were recorded from 16 subjects in each of the following age groups, 5-7, 9-11, 14-16, and 20-28 years of age. Subjects performed a novelty oddball task, in which frequent, standard tones (80% probability) were intermixed with infrequent tones to which the subject responded (10%), along with 48 unique novel, environmental sounds (10%). Analyses focused on the effects of temporal order (either serial order within the block or block number) in interaction with age group on the ERPs to the novel sounds. The amplitude and scalp distribution of two ERP components were analyzed, the 'novelty P3,' assumed to reflect aspects of the orienting response, and the P3(2), a component that may be synonymous with the P3b. Evidence suggests that the frontal aspect of the scalp distribution of the novelty P3 depends upon the integrity of the prefrontal cortex. Temporal order produced systematic (primarily linear) reductions in novelty P3 amplitude that were greater at frontal than posterior electrode sites. The P3(2) did not show consistent effects of temporal order. Both of these phenomena were highly similar for all four age groups. It is concluded that the brain's response to novelty is similar across a wide age range, involving a neural circuit with both frontal and posterior elements. (C) 1997 Elsevier Science Ireland Ltd.