Prevalence of symptoms among patients with advanced cancer: An international collaborative study
Prevalence of symptoms among patients with advanced cancer: An international collaborative study
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DOI：
10.1016/0885-3924(96)00042-5
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发表时间：
1996-07-01
影响因子：
4.7
通讯作者：
Morant, R
中科院分区：
文献类型：
--
作者：
Vainio, A;Auvinen, A;Morant, R
本研究的目的是(a)估计来自不同姑息治疗中心的大量晚期癌症患者中疼痛和其他八种常见症状的患病率，以及(b)评估原发部位的症状患病率差异。在1990-1991年间，对欧洲、美国和澳大利亚的7所临终关怀医院的1840名癌症患者进行了8种主要症状的患病率和表现状况的前瞻性评估。在每个机构使用世界卫生组织（世卫组织）癌症和姑息治疗股的结构化数据收集表收集数据。中度至重度疼痛的患病率为51%，从胃癌的43%到妇科癌症的80%不等。恶心在妇科癌症（42%）和胃癌（36%）中最为普遍，而呼吸困难在肺癌（46%）中最为普遍。根据癌症原发部位和安宁疗护不同，大多数症状的发生率有统计学显著差异，需要基于人群的随访研究来记录整个疾病过程中症状的发生率和患病率。
The aims of this study were (a) to estimate the prevalence of pain and eight other common symptoms in a large population of patients with advanced cancer from different palliative care centers, and (b) to assess the differences in prevalence of the symptoms by primary site. In 1990-1991, the prevalence of eight major symptoms and performance status were assessed prospectively among 1840 cancer patients in seven hospices in Europe, the United States, and Australia. The data were collected at each institution using structured data collection sheets from the World Health Organization's (WHO) Cancer and Palliative Care Unit. The prevalence of moderate to severe pain was 51%, ranging from 43% in stomach cancer to 80% in gynecological cancers. Nausea was most prevalent in gynecological (42%) and stomach (36%) cancers, and dyspnea (46%) in lung cancer There were statistically significant differences in the prevalence of most symptoms depending on the primary site of cancer and the hospice, Population-based follow-up studies are needed to document the incidence and prevalence of symptoms throughout the course of the disease.