Dermoscopy of pigmcnted seborrheic keratosis - A morphological study

Dermoscopy of pigmcnted seborrheic keratosis - A morphological study
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DOI:
10.1001/archderm.138.12.1556
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发表时间:
2002-12-01
影响因子:
--
通讯作者:
Saurat, JH
Saurat, JH
中科院分区:
其他
文献类型:
--
作者:
Braun, RP;Rabinovitz, HS;Saurat, JH

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目的:为了。描述了通过皮肤镜观察到的脂溢性角化病的形态学特征,并调查其患病率。设计:使用宏观摄影和皮肤镜记录脂溢性角化病的前瞻性队列研究。设置:在2个地点前瞻性收集脂溢性角化病:弗拉种植园的私人诊所(地点1)和瑞士日内瓦大学医院皮肤科(地点2)。患者:203例色素性脂溢性角化病(来自192名患者),收集了完整的记录(111例来自1号站点,93例来自2号站点)。干预措施:筛选脂溢性角化病的新形态学特征,并评估所有病变的这些标准的患病率。主要结果测量:识别新形态学标准并评估频率。结果:共确定了15个形态学皮肤镜标准。在大量病例中发现了标准,如粟粒样囊肿和粉刺样开口(分别为135和144)。我们发现网络和网络状结构存在于94个病灶(46%)。使用标准的诊断标准,脂溢性角化病,30病变不会被诊断为suse.Conclusions:经典的皮肤镜标准,脂溢性角化病(粟粒样囊肿和粉刺样开口)有很高的患病率,但使用额外的皮肤镜标准,如裂缝,发夹血管,尖锐的分界线,和虫蛀的边界提高了诊断的准确性。正确识别色素网络和网络样结构对于正确诊断是重要的。
Objectives: To. describe morphological features of seborrheic keratosis as seen by dermoscopy and to investigate their prevalence.Design: Prospective cohort study using macrophotography and dermoscopy for the documentation of seborrheic keratosis.Settings: Seborrheic keratoses were prospectively collected in 2 sites: a private practice in Plantation, Fla (site 1), and the Department of Dermatology at the University Hospital Geneva in Switzerland (site 2).Patients: A total of 203 pigmented seborrheic keratoses (from 192 patients) with complete documentation were collected (111 from site 1 and 93 from site 2).Interventions: Screening for new morphological features of seborrheic keratosis and evaluation of all lesions for the prevalence of these criteria.Main Outcome Measures: Identification of new morphological criteria and evaluation of frequency.Results: A total of 15 morphological dermoscopic criteria were identified. Standard criteria such as milialike cysts and comedolike openings were found in a high number of cases (135 and 144, respectively). We found network and networklike structures to be present in 94 lesions (46%). Using standard diagnostic criteria for seborrheic keratosis, 30 lesions would not have been diagnosed as such.Conclusions: The classic dermoscopic criteria for seborrheic keratosis (milialike cysts and comedolike openings) have a high prevalence but the use of additional dermoscopic criteria such as fissures, hairpin blood vessels, sharp demarcation, and moth-eaten borders improves the diagnostic accuracy. The proper identification of pigment network and networklike structures is important for the correct diagnosis.