Patients and nonconsulters with irritable bowel syndrome reporting a parental history of bowel problems have more impaired psychological distress
Patients and nonconsulters with irritable bowel syndrome reporting a parental history of bowel problems have more impaired psychological distress
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DOI：
10.1023/b:ddas.0000034570.52305.10
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发表时间：
2004-06-01
影响因子：
3.1
通讯作者：
Fukudo, S
中科院分区：
文献类型：
--
作者：
Kanazawa, M;Endo, Y;Fukudo, S
日本肠易激综合征（IBS）的患病率和危险因素知之甚少。在美国，据报道，遗传和社会学习有助于IBS的发展。我们的目的是（1）估计IBS的患病率，（2）证实IBS患者的父母更有可能有肠道疾病史，（3）证实胃肠炎是IBS的一个危险因素，（4）确定这两个危险因素是否与心理困扰相互作用。患病率是从417名年轻人的样本进行年度健康筛查检查。为了评估与咨询医生相关的风险因素，将46名符合罗马II IBS诊断标准但否认曾因这些症状就诊的受试者（IBS非咨询者）与317名不符合IBS标准的受试者（对照组）和56名胃肠病学家诊断为IBS的患者（IBS患者）进行比较。所有受试者完成了胃肠道症状评定量表、状态-特质焦虑量表、抑郁自评量表、感知压力量表和SF-36生活质量量表。14.2%的社区样本（15.5%的女性和12.9%的男性）符合IBS诊断标准，其中22%咨询了医生。IBS患者和IBS非咨询者比对照组更可能有父母病史（33.9%对12.6%，P
Little is known about the prevalence and risk factors for development of irritable bowel syndrome (IBS) in Japan. In the United States, it is reported that heredity and social learning contribute to the development of IBS. Our aims were (1) to estimate the prevalence of IBS, (2) to confirm that subjects with IBS are more likely to have parents with a history of bowel problems, (3) to confirm that gastroenteritis is a risk factor for IBS, and (4) to determine whether these two risk factors interact with psychological distress. Prevalence was estimated from a sample of 417 young adults seen for annual health screening examinations. To evaluate risk factors related to consulting physicians, the 46 subjects who fulfilled Rome II diagnostic criteria for IBS but denied ever having seen a physician about these symptoms (IBS non-consulters) were compared to the 317 subjects who did not meet the criteria for IBS (controls) and to a group of 56 patients diagnosed with IBS by gastroenterologists (IBS patients). All subjects completed the Gastrointestinal Symptoms Rating Scale, the State-Trait Anxiety Inventory, the Self-Rating Depression Scale, the Perceived Stress Scale, and the SF-36 quality of life scale. Fourteen and two-tenths percent (15.5% of females and 12.9% of males) of the community sample met the criteria for IBS diagnosis, of whom 22% consulted physicians. IBS patients and IBS nonconsulters were more likely than controls to have a parental history (33.9 vs. 12.6%, P