An evaluation of the impact of a community-based adherence support programme on ART outcomes in selected government HIV treatment sites in South Africa

An evaluation of the impact of a community-based adherence support programme on ART outcomes in selected government HIV treatment sites in South Africa
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DOI:
10.1080/09540121.2010.498909
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发表时间:
2011-01-01
影响因子:
1.7
通讯作者:
Grimwood, A.
Grimwood, A.
中科院分区:
医学4区
文献类型:
--
作者:
Igumbor, J. O.;Scheepers, E.;Grimwood, A.

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本研究评估了基于社区的依从性支持服务对接受抗逆转录病毒治疗(ART)患者结局的影响。该评价是一项基于患者临床记录的回顾性研究。这项研究指出,一个显着更高比例的患者与社区为基础的坚持支持者,(也称为患者倡导者,PA)在治疗6个月时病毒载量(VL)低于400拷贝/ml(70%,p = 0.001);显著较高比例的PA患者(89%)获得了超过95%(67%; p = 0.021)的治疗选择率。与没有PA服务的卫生机构的患者相比,在有PA服务的卫生机构的患者在更长时间内保持了受抑制的VL(p = 0.001),并且在有PA服务的卫生机构的患者在更长时间内保持了护理(p = 0.001)。因此,该研究得出结论,基于社区的综合依从性支持对于确保患者继续接受护理,定期从ART诊所接受治疗并在病毒学上受到抑制至关重要。研究报告还强调了获得保健服务的重要性,以及在治疗艾滋病方面存在一个有利的环境。
This study assessed the impact of a community-based adherence support service on the outcomes of patients on antiretroviral therapy (ART). The evaluation was a retrospective study based on patient clinical records. This study noted that a significantly higher proportion of patients with a community-based adherence supporter (also known as a patient advocate, PA) had viral load (VL) of less than 400 copies/ml at six months of treatment (70%, p = 0.001); a significantly higher proportion of patients with PAs (89%) attained a treatment pickup rate of over 95% (67%; p = 0.021). Patients at health facilities with PA services maintained a suppressed VL for a longer period as opposed to patients at health facilities without PA services (p = 0.001), also patients at health facilities with PA services remained in care for longer periods (p = 0.001). Therefore, the study concludes that integrated community-based adherence support is crucial in ensuring that patients remain in care, regularly pickup their treatment from ART clinics and are virologically suppressed. The study also underscores the importance of access to health services and the presence of an enabling environment in the treatment of AIDS.