Pulmonary responses to oil fly ash particles in the rat differ by virtue of their specific soluble metals
Pulmonary responses to oil fly ash particles in the rat differ by virtue of their specific soluble metals
复制标题
DOI：
10.1093/toxsci/43.2.204
复制
发表时间：
1998-06-01
影响因子：
3.8
通讯作者：
Costa, DL
中科院分区：
文献类型：
--
作者：
Kodavanti, UP;Hauser, R;Costa, DL
职业暴露于残油飞灰（ROFA）颗粒与人类呼吸系统健康的不良影响。我们假设，ROFA收集在不同地点的石油燃烧发电厂，凭借其不同的金属和硫酸盐的组成，将诱导差异性肺损伤。十个ROFA样品收集在不同的网站内的发电厂进行了分析，水和1.0 M盐酸浸出砷（As），铍（Be），镉（Cd），钴（Co），铬（Cr），铜（Cu），铁（Fe），锰（Mn），镍（Ni），铅（Pb），钒（V），锌（Zn），和硫的电感耦合等离子体原子发射光谱法。所有ROFA样品均含有不同量的沥滤物（水浸提物）和1.0 M HCl浸提物Fe、V和/或Ni。除Zn（ROFA 1号含3.43 μ g/mg Zn，ROFA 3号含6.35 μ g/mg Zn）外，所有其他金属的含量可忽略不计（
Occupational exposure to residual oil fly ash (ROFA) particulate has been associated with adverse respiratory health effects in humans. We hypothesized that ROFA collected at different sites within an oil burning power plant, by virtue of its differing metal and sulfate composition, will induce differential lung injury. Ten ROFA samples collected at various sites within a power plant were analyzed for water- and 1.0 M HCl-leachable arsenic (As), beryllium (Be), cadmium (Cd), cobalt (Co), chromium (Cr), copper (Cu), iron (Fe), manganese (Mn), nickel (Ni), lead (Pb), vanadium (V), zinc (Zn), and sulfur by inductively coupled plasma-atomic emission spectroscopy. All ROFA samples contained variable amounts of leachable (water-extractable) and 1.0 M HCl-extractable Fe, V, and/or Ni. All other metals, except Zn (ROFA No. 1 contained 3.43 and No. 3, 6.35 mu g/mg Zn), were present in negligible quantities (