Integration of monolithic porous polymer with droplet-based microfluidics on a chip for nano/picoliter volume sample analysis.
Integration of monolithic porous polymer with droplet-based microfluidics on a chip for nano/picoliter volume sample analysis.
复制标题
将单片多孔聚合物与液滴基于基于液滴的微流体的集成在芯片上进行纳米/picoliter体积样品分析。
DOI：
10.1186/s40580-014-0003-9
复制
发表时间：
2014
期刊：
影响因子：
11.7
通讯作者：
O'Hare D
中科院分区：
文献类型：
--
作者：
Kim JY;Chang SI;deMello AJ;O'Hare D
在本文中，多孔聚合物纳米结构与基于液滴的微流体以单一平面形式集成。在微流体通道内选择性地形成整体多孔聚合物（MPP）。所得到的分析物条带随后被共价化成液滴。该装置通过结合两种技术来减少谱带展宽和柱后死体积的影响。此外，它还提供纳/皮升体积样品的精确控制。
In this paper, a porous polymer nanostructure has been integrated with droplet-based microfluidics in a single planar format. Monolithic porous polymer (MPP) was formed selectively within a microfluidic channel. The resulting analyte bands were sequentially comartmentalised into droplets. This device reduces band broadening and the effects of post-column dead volume by the combination of the two techniques. Moreover it offers the precise control of nano/picoliter volume samples.