LPA in neural cell development
LPA in neural cell development
复制标题
DOI：
10.1002/jcb.20093
复制
发表时间：
2004-08-01
影响因子：
4
通讯作者：
Fukushima, N
中科院分区：
文献类型：
--
作者：
Fukushima, N
溶血磷脂酸（LPA）通过神经系统来源的细胞和细胞系中的细胞表面LPA受体引起多种细胞反应。发育中的神经系统是LPA受体表达的主要位点之一。最近的研究还表明，LPA的代谢途径存在于神经系统中。越来越多的文献表明LPA在神经元发育过程中起着至关重要的作用，包括神经发生、神经元迁移、轴突发生和髓鞘形成。(C)2004 Wiley-Liss，Inc.
Lysophosphatidic acid (LPA) elicits diverse cellular responses through cell surface LPA receptors in nervous system-derived cells and cell lines. The developing nervous system is one of the major loci for LPA receptor expression. Recent studies have also revealed that metabolic pathways of LPA are present in the nervous system. A growing body of literature Suggests a crucial role for LPA in neuronal development processes, including neurogenesis, neuronal migration, neuritogenesis, and myelination. (C) 2004 Wiley-Liss, Inc.