Patient-rating of distressful symptoms after treatment for early cervical cancer
Patient-rating of distressful symptoms after treatment for early cervical cancer
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DOI：
10.1034/j.1600-0412.2002.810512.x
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发表时间：
2002-05-01
影响因子：
4.3
通讯作者：
Steineck, G
中科院分区：
文献类型：
--
作者：
Bergmark, K;Åvall-Lundqvist, E;Steineck, G
背景。关于患者群体中症状引起的痛苦来源的更精细的信息可以提高治疗前信息的质量，使随访更加有效，并指导修改治疗方法的研究重点。方法。在一项涵盖瑞典全境的人口流行病学研究中，1996-97 年通过匿名邮寄调查问卷收集了数据。我们试图招募 1991-92 年在瑞典七个妇科肿瘤科登记的全部 332 名 IB-IIA 期宫颈癌患者。结果。共有 256 例（77%）完成了问卷。手术后，单独或与腔内放疗联合，与性功能障碍相关的几种症状是症状引起的痛苦性高潮频率降低的主要原因：严重痛苦分别为 23%（单独手术）和 23%（腔内放疗和手术），总体性交功能障碍：严重痛苦分别为 17% 和 20%，其次是淋巴水肿（严重痛苦分别为 14% 和 14%）。性交困难（严重痛苦 24%）和排便急迫（严重痛苦 22%）是手术和外部放疗后造成痛苦的两个主要原因。单纯放射治疗后，稀便和性交困难是两种最令人痛苦的症状（各占 19%）。当症状出现时，粪便渗漏和性高潮频率降低是最令人痛苦的两个（测量同样多的痛苦，各占 38%）。结论。观察到的症状令人痛苦，如果关注患者满意度，应优先考虑。
Background. More refined information on sources of symptom-induced distress in a patient population can improve the quality of pretreatment information, make follow-up visits more efficient and guide research priorities in the efforts to modify treatments.Methods. In a population-based epidemiological study covering all of Sweden, data were collected 1996-97 by means of an anonymous postal questionnaire. We attempted to enroll all 332 patients with stage IB-IIA cervical cancer registered in 1991-92 at the seven departments of gynecological oncology in Sweden.Results. A total of 256 cases (77%) completed the questionnaire. After surgery, alone or in combination with intracavitary radiotherapy, several symptoms related to sexual dysfunction are the primary sources of symptom-induced distress reduced orgasm frequency: much distress 23% (surgery alone) and 23% (intracavitary radiotherapy and surgery), respectively, overall intercourse dysfunction: much distress 17% and 20%, respectively, followed by lymphedema (much distress 14% and 14%, respectively). Dyspareunia (much distress 24%) and defecation urgency (much distress 22%) are two leading causes of distress after surgery and external radiotherapy. After treatment with radiotherapy alone, loose stool and dyspareunia were the two most distressful symptoms (much distress 19% each). When a symptom occurs, fecal leakage and reduced orgasm frequency are the two most distressful ones (measured as much distress, 38% each).Conclusions. The observed symptoms are distressful and should, if one focuses on patient satisfaction, be given priority.