Electrophysiological characteristics of fetal atrioventricular block
Electrophysiological characteristics of fetal atrioventricular block
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DOI：
10.1016/j.jacc.2007.06.060
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发表时间：
2008-01-01
影响因子：
24
通讯作者：
Wakai, Ronald T.
中科院分区：
文献类型：
--
作者：
Zhao, Hui;Cuneo, Bettina F.;Wakai, Ronald T.
目的我们的工作的目的是确定复杂的电生理特征，在第二次-（2度）和3度（3度）房室传导阻滞（AVB）并纵向跟踪心房和心室心率和节律模式的发展，目的是识别与紧急分娩或新生儿起搏相关的心率和节律模式。出生前AVB尚未得到广泛研究，但这种疾病的死亡率很高。沿着胎儿治疗和干预的进展，需要对AVB病因的全面自然史以及影响结果的电生理因素进行最佳选择治疗方案。方法28例AVB胎儿进行了胎儿心磁图评估; 21例胎儿进行了连续评估。1）2度AVB期间不同的房性节律和房室传导机制; 2）3度AVB期间交界性异位心动过速和室性心动过速; 3）心室率>56次/min时反应性心室和心房胎心率（FHR）描记; 4）心室率时平坦心室FHR描记
Objectives The purpose of our work was to define the complex electrophysiological characteristics seen in second- (2 degrees) and third-degree (3 degrees) atrioventricular block (AVB) and to longitudinally follow the development of atrial and ventricular heart rate and rhythm patterns with a goal of identifying heart rate and rhythm patterns associated with urgent delivery or neonatal pacing.Background The electrophysiological characteristics of congenital AVB before birth have not been extensively studied, yet the mortality from this disease is substantial. Along with advances in fetal therapies and interventions, a comprehensive natural history specific to the etiology of AVB, as well as the electrophysiological factors influencing outcome, are needed to best select treatment options.Methods Twenty-eight fetuses with AVB were evaluated by fetal magnetocardiography; 21 fetuses were evaluated serially.Results Fetuses with 2 degrees AVB and isolated 3 degrees AVB showed: 1) diverse atrial rhythms and mechanisms of atrioventricular conduction during 2 degrees AVB; 2) junctional ectopic tachycardia and ventricular tachycardia during 3 degrees AVB; 3) reactive ventricular and atrial fetal heart rate (FHR) tracings at ventricular rates >56 beats/min; and 4) flat ventricular FHR tracings at ventricular rates