Effect of the degree of effort on the sensitivity of the exercise thallium-201 stress test in symptomatic coronary artery disease.
Effect of the degree of effort on the sensitivity of the exercise thallium-201 stress test in symptomatic coronary artery disease.
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努力程度对有症状冠状动脉疾病运动铊 201 压力测试敏感性的影响。
DOI：
10.1016/0002-9149(89)90278-6
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发表时间：
1989
期刊：
影响因子：
--
通讯作者：
Kaul,S
中科院分区：
文献类型：
--
作者：
Esquivel,L;Pollock,SG;Beller,GA;Gibson,RS;Watson,DD;Kaul,S
运动时心电图ST段压低的敏感性受运动强度的影响。至于铊-201成像（初始缺陷或再分布）是否如此，尚未确定。因此，在288例冠状动脉疾病患者（年龄59 ± 10岁，88%为男性）中评价了这些参数的患病率，这些患者在3个月内接受了运动铊-201成像和冠状动脉血管造影术：159例既往心肌梗死，72例单支血管病变，216例多支血管病变。通过3个标准评估努力程度：（1）最大预测心率百分比（≤ 65，> 65至85，> 85%）;（2）运动期间的工作负荷（≤ 4，> 4至8，> 8 MET）;和（3）运动持续时间（≤ 3，> 3至6，> 6分钟）。初始图像缺陷的患病率高于延迟图像再分布和心电图ST段压低（p < 0.01）。初始缺陷的总体患病率在所有水平的努力下保持不变，并且不受既往是否存在梗死的影响。然而，在运动负荷较高的单支血管疾病患者中，它降低了。铊-201延迟显像的再分布发生率高于心电图ST段压低发生率（p < 0.01），但在更高水平的努力时两者相似。这种在高水平努力下再分布发生率的降低主要发生在既往有梗死或单支血管病变的患者中。得出的结论是，铊-201成像（初始缺陷和再分布）的异常结果的总体患病率并没有显着影响的努力程度的患者进行限制性运动试验。由于在大多数患者中，与ST段压低相比，这些发现的产率更高，因此应将铊-201成像添加到常规运动负荷试验中以检测冠状动脉疾病，
The sensitivity of ST-segment depression on the electrocardiogram during exercise is influenced by the level of effort. Whether such is the case with thallium-201 imaging (initial defect or redistribution) has not been established. Accordingly, the prevalence of these parameters was evaluated in 288 patients (age 59 ± 10 years, 88% men) with coronary artery disease who underwent both exercise thallium-201 imaging and coronary anglography within 3 months of each other: 159 had a prior myocardial infarction, 72 had 1-vessel, and 216 had multivessel disease. The degree of effort was evaluated by 3 criteria: (1) percentage of maximal predicted heart rate (≤ 65, > 65 to 85, > 85%); (2) workload during exercise (≤ 4, > 4 to 8, > 8 METs); and (3) duration of exercise (≤ 3, > 3 to 6, > 6 minutes). The prevalence of defects on initial images was higher than both redistribution on delayed images and ST-segment depression on the electrocardiogram (p < 0.01). The overall prevalence of initial defects remained the same for all levels of effort and was not influenced by the presence or absence of a prior infarction. However, it decreased in patients with 1-vessel disease who exercised to higher workloads. The prevalence of redistribution on delayed thallium-201 images was higher than that of ST-segment depression on the electrocardiogram (p < 0.01), except at higher levels of effort where they were similar. This decrease in the prevalence of redistribution at high levels of effort occurred predominantly in patients with a prior infarction or those with 1-vessel disease. It was concluded that the overall prevalence of abnormal findings on thallium-201 imaging (initial defect and redistribution) is not significantly affected by the degree of effort in patients undergoing symptom-limited exercise testing. Because of the higher yield of these findings compared with ST-segment depression in most patients, thallium-201 imaging should be added to routine exercise stress testing for the detection of coronary artery disease,
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运动铊 201 试验对胸痛门诊患者的预后效用：与心导管插入术的比较。
影响因子：
37.8
作者：
Kaul,S;Lilly,DR;Gascho,JA;Watson,DD;Gibson,RS;Oliner,CA;Ryan,JM;Beller,GA
通讯作者：
Beller,GA
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DOI：
10.1016/0002-9149(85)90845-8
发表时间：
1985
期刊：
The American journal of cardiology
影响因子：
--
作者：
Kaul,S;Kiess,M;Liu,P;Guiney,TE;Pohost,GM;Okada,RD;Boucher,CA
通讯作者：
Boucher,CA
正常人群中缺血运动心电图的产量与运动强度的关系。
影响因子：
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作者：
G. Cumming
通讯作者：
G. Cumming
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影响因子：
37.8
作者：
J. Melin;L. Piret;R. Vanbutsele;M. Rousseau;J. Cosyns;L. Brasseur;C. Beckers;J. Detry
通讯作者：
J. Detry
运动铊图像的计算机分析在冠状动脉疾病无创检测中的价值。
DOI：
--
发表时间：
1986
期刊：
Journal of the American Medical Association (JAMA)
影响因子：
--
作者：
S. Kaul;J. Newell;D. Chesler;G. Pohost;R. Okada;T. Guiney;C. Boucher
通讯作者：
C. Boucher