New phenolic components from Daphne giraldii
New phenolic components from Daphne giraldii
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DOI：
10.1002/hlca.200590230
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发表时间：
2005-01-01
影响因子：
1.8
通讯作者：
Yue, JM
中科院分区：
文献类型：
--
作者：
Liao, SG;Zhang, BL;Yue, JM
从瑞香叶和茎中分离得到两个新的双香豆素，分别为瑞香素(1)、瑞香素(2)和黄烷-3-醇衍生物5-O-甲基瑞香素(3)，以及11个已知化合物瑞香素、12-二氢瑞香素、异甲肾上腺素trans-2，3-dihydro-3-(4-hydroxy-3-methoxphenyl)-2-(hydroxymethyl)-9H-pyrano[2，3-f]-1，4-benzodioxin-9-one(4b)、(+)-松脂醇、阿克米丁、(-)-二氢芝麻素和异水杨叶素。化合物4b为首次从瑞香中分离得到的天然产物，其中1，2-二氢瑞香素、瑞香素、异月桂素、(+)-松脂醇、乌头素、(-)-二氢芝麻素和异水杨叶素为首次从瑞香中分离得到。通过波谱分析确定了三个新化合物的结构。
Two new bis-coumarins, namely daphnogitin (1), daphnogirin (2), and a flavan-3-ol derivative, 5-O-methylafzelechin (3), together with eleven known compounds, daphnetoxin, 12-dihydrodaphrictoxin, daphnetin, daphnoretin, daphneticin, isosaphneticine trans-2,3-dihydro-3-(4-hydroxy-3-methoxphenyl)-2-(hydroxymethyl)-9H-pyrano[2,3-f]-1,4-benzodioxin-9-one (=demethoxyisodaphneticin; 4b), (+)-pinoresinol, acuminatin, (-)-dihydrosesamin, and isosalicifoline, were isolated from the leaves and stems of Daphne giraldii. Compound 4b was isolated for the first time as a natural product, and 1,2-dihydrodaphrietoxin, daphneticin, isodaphneticin, (+)-pinoresinol, acuminatin, (-)-dihydrosesamin, and isosalicifoline were isolated for the first time from Daphne giraldii. The structures of the three new compounds were elucidated by spectroscopic analysis.