Genetic basis of ecologically relevant body shape variation among four genera of cichlid fishes.
Genetic basis of ecologically relevant body shape variation among four genera of cichlid fishes.
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慈鲷四个属生态相关体形变异的遗传基础。
DOI：
10.1111/mec.16977
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发表时间：
2023
影响因子：
4.9
通讯作者：
Powder,KaraE
中科院分区：
文献类型：
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作者：
DeLorenzo,Leah;Mathews,Destiny;Brandon,AAllyson;Joglekar,Mansi;CarmonaBaez,Aldo;Moore,EmilyC;Ciccotto,PatrickJ;Roberts,NatalieB;Roberts,ReadeB;Powder,KaraE
体形的分化是鱼类形态变异中最广泛和重复的模式之一，与栖息地规范和游泳力学有关。这种生态多样化是东非裂湖慈鲷适应性辐射爆发性的第一阶段。我们使用丽鱼科鱼的两种杂交杂交（Metriaclimasp.×Aulonocarasp. 和 Labidochromissp.×Labeotropeussp.，总共 > 975 只动物）来确定与鱼类之间的底栖-中上层分化相似的体形多样化的遗传基础。通过一系列线性和几何形状测量，我们确定了 34 个数量性状基因座 (QTL)，它们是体型变异各个方面的基础。这些 QTL 分布在整个基因组中，每个 QTL 解释 3.2-8.6% 的表型变异，并且很大程度上是模块化的。此外，马拉维湖丽鱼科鱼的这两个杂交之间以及与之前确定的刺鱼等鱼类体形的 QTL 相比，QTL 都是不同的。我们发现体型是由许多影响较小的基因控制的。总之，我们发现在鱼类进化枝中常见的趋同体形表型很可能是由于不同的遗传和分子机制造成的。
Divergence in body shape is one of the most widespread and repeated patterns of morphological variation in fishes and is associated with habitat specification and swimming mechanics. Such ecological diversification is the first stage of the explosive adaptive radiation of cichlid fishes in the East African Rift Lakes. We use two hybrid crosses of cichlids (Metriaclimasp.×Aulonocarasp. andLabidochromissp.×Labeotropheussp., >975 animals total) to determine the genetic basis of body shape diversification that is similar to benthic‐pelagic divergence across fishes. Using a series of both linear and geometric shape measurements, we identified 34 quantitative trait loci (QTL) that underlie various aspects of body shape variation. These QTL are spread throughout the genome, each explaining 3.2–8.6% of phenotypic variation, and are largely modular. Further, QTL are distinct both between these two crosses of Lake Malawi cichlids and compared to previously identified QTL for body shape in fishes such as sticklebacks. We find that body shape is controlled by many genes of small effect. In all, we find that convergent body shape phenotypes commonly observed across fish clades are most likely due to distinct genetic and molecular mechanisms.