The Impact of Sleep on Neurocognition and Functioning in Schizophrenia-Is It Time to Wake-Up?
The Impact of Sleep on Neurocognition and Functioning in Schizophrenia-Is It Time to Wake-Up?
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DOI：
10.20900/jpbs.20220001
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发表时间：
2022-01-01
期刊：
影响因子：
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通讯作者：
Varga, Andrew W
中科院分区：
文献类型：
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作者：
Kimhy, David;Ospina, Luz;Varga, Andrew W
精神分裂症 (SZ) 患者表现出严重的神经认知缺陷，这被认为是日常功能不佳和残疾的主要原因。之前的报告已经确定了深圳地区神经认知能力差的许多预测因素，包括人口统计、症状和治疗依从性，以及体重指数、有氧健身和运动活动。然而，尽管睡眠障碍在该人群中普遍存在，导致的症状与深圳常见的神经认知缺陷惊人相似，但人们对睡眠的假定影响的考虑相对有限。在这里，我们主张考虑睡眠对精神分裂症患者神经认知的影响，并为未来的研究提出建议，以阐明睡眠参数、神经认知和日常功能之间的联系。
People with schizophrenia (SZ) display substantial neurocognitive deficits that have been implicated as major contributors to poor daily functioning and disability. Previous reports have identified a number of predictors of poor neurocognition in SZ including demographics, symptoms, and treatment adherence, as well as body mass index, aerobic fitness, and exercise activity. However, the putative impact of sleep has received relatively limited consideration, despite sleep disturbances, which are pervasive in this population, resulting in symptoms that are strikingly similar to the neurocognitive deficits commonly observed in SZ. Here we argue for the consideration of the impact of sleep on neurocognition in people with SZ and propose recommendations for future research to elucidate the links between sleep parameters, neurocognition and daily functioning.