Avian influenza antibody detection by immunodiffusion.

Avian influenza antibody detection by immunodiffusion.
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免疫扩散法检测禽流感抗体。

DOI:
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发表时间:
1970
期刊:
影响因子:
1.4
通讯作者:
C. Beard
C. Beard
中科院分区:
农林科学4区
文献类型:
--
作者:
C. Beard

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现场暴发后,通过琼脂凝胶沉淀素(AGP)试验在火鸡血清中证实了流感抗体的恢复水平。在实验室暴露于3种流感病毒株中的任何一种后,鸡血清的AGP试验呈阳性至少8周,火鸡血清的AGP试验呈阳性至少12周。AGP检测有助于使用可疑病毒或配对血清诊断禽流感,而不会受到毒株间抗原差异的影响,这些差异限制了血凝抑制试验的有用性。
Convalescent levels of influenza antibodies were demonstrated by an agar gel precipitin (AGP) test in turkey sera after field outbreaks. The AGP test was positive with chicken sera for at least 8 weeks after laboratory exposure to any of 3 influenza strains, and positive with turkey sera for at least 12 weeks after exposure. The AGP test facilitates a diagnosis of avian influenza using a suspect virus or paired sera without the influences of strain-to-strain antigenic differences, which limit the usefulness of the hemagglutination-inhibition test.