Multidimensional Sleep Health Is Associated with Cardiovascular Disease Prevalence and Cardiometabolic Health in US Adults.

Multidimensional Sleep Health Is Associated with Cardiovascular Disease Prevalence and Cardiometabolic Health in US Adults.
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DOI:
10.3390/ijerph191710749
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发表时间:
2022-08-29
影响因子:
--
通讯作者:
Tehranifar, Parisa
Tehranifar, Parisa
中科院分区:
综合性期刊3区
文献类型:
--
作者:
Makarem, Nour;Alcantara, Carmela;Musick, Sydney;Quesada, Odayme;Sears, Dorothy D.;Chen, Ziyu;Tehranifar, Parisa

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个体睡眠的各个维度与心血管疾病(CVD)风险和心脏代谢健康(CMH)相关,但睡眠健康是多方面的。我们研究了多维睡眠健康(MDSH)评分与心血管疾病和心脏代谢健康的关联,该评分能够评估睡眠健康梯度。参与者是来自2017 - 2018年美国国家健康与营养检查调查的4555名年龄≥20岁的成年人。MDSH评分是根据自我报告的睡眠时间、睡眠规律、入睡困难、睡眠障碍症状和日间嗜睡情况计算得出的,它涵盖了差、中等和理想的睡眠状况。调查加权的多变量线性和逻辑回归模型检验了MDSH与心血管疾病和心脏代谢健康的关联。理想和中等的MDSH(与差的相比)分别与较低的高血压患病几率(62%和41%)、肥胖症患病几率(73%和56%)以及中心性肥胖患病几率(68%和55%)相关;在MDSH的各个梯度中观察到了具有统计学意义的线性趋势(趋势p值<0.001)。理想的MDSH(与中等/差的相比)分别与现患心血管疾病和2型糖尿病的患病几率低32%和40%相关。更有利的MDSH与较低的血压、体重指数、腰围和空腹血糖相关。在按性别分层的分析中,理想的MDSH(与中等/差的相比)仅在女性中与较低的心血管疾病患病几率和血压相关。MDSH框架可能不仅仅是其各部分的总和,它可以更好地获取有关心血管疾病风险的信息。
Individual sleep dimensions have been linked to cardiovascular disease (CVD) risk and cardiometabolic health (CMH), but sleep health is multifaceted. We investigated associations of a multidimensional sleep health (MDSH) score, enabling the assessment of sleep health gradients, with CVD and CMH. Participants were 4555 adults aged ≥20 years from the 2017–2018 National Health and Nutrition Examination Survey. A MDSH score, capturing poor, moderate, and ideal sleep was computed from self-reported sleep duration, sleep regularity, difficulty falling asleep, symptoms of sleep disorders, and daytime sleepiness. Survey-weighted multivariable linear and logistic models examined associations of MDSH with CVD and CMH. Ideal and moderate vs. poor MDSH were related to lower odds of hypertension (62% and 41%), obesity (73% and 56%), and central adiposity (68% and 55%), respectively; a statistically significant linear trend was observed across gradients of MDSH (p-trend < 0.001). Ideal vs. moderate/poor MDSH was associated with 32% and 40% lower odds of prevalent CVD and type 2 diabetes, respectively. More favorable MDSH was associated with lower blood pressure, BMI, waist circumference, and fasting glucose. In sex-stratified analyses, ideal vs. moderate/poor MDSH was associated with lower CVD odds and blood pressure in women only. The MDSH framework may be more than just the sum of its parts and could better capture information regarding CVD risk.
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