Establishment of a global virtual laboratory for transplantation: a symposium report.
Establishment of a global virtual laboratory for transplantation: a symposium report.
复制标题
全球移植虚拟实验室的建立：研讨会报告。
DOI：
10.1097/tp.0000000000000560
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发表时间：
2015-02
期刊：
影响因子：
6.2
通讯作者：
Chong AS
中科院分区：
文献类型：
--
作者：
Geissler EK;Tullius SG;Chong AS
Advancing the field of transplantation by developing improved and novel treatment strategies will require a detailed understanding of changes and adaptations of alloimmunity, both over the short and long-term. Presently, we rely on traditional measures that may not optimally reflect benefits of new treatments. Thus, collecting reliable basic information about changes of the immune response along the entire post-transplantation course will improve our understanding of how immune mechanisms evolve and guide the introduction of novel clinical approaches. The gathering of good quality data from transplant recipients in various clinical trials will require immune monitoring that is reliable and comparable so that large sets of information from individual trials can be confidently analyzed to reach rigorous conclusions. A uniform standard of testing is thus a prerequisite towards this goal. Based on the assumption that the transplantation community will in general be supportive of this concept, this meeting proposed establishing a Global Virtual Laboratory (GVL) as a means of developing and disseminating detailed and rigorous protocols for the monitoring of alloimmune responses.
