Dietary, Nutrient Patterns and Blood Essential Elements in Chinese Children with ADHD.
Dietary, Nutrient Patterns and Blood Essential Elements in Chinese Children with ADHD.
复制标题
中国多动症儿童的膳食、营养模式和血液必需元素
作者：
Zhou F;Wu F;Zou S;Chen Y;Feng C;Fan G
膳食或营养模式代表了食物或营养素的综合作用，并有效地阐明了饮食对疾病的影响。由于注意缺陷多动障碍（ADHD）的药物治疗有一定的副作用，而ADHD的病因是多因素的，因此本研究探讨了饮食和营养模式与ADHD风险的关系。我们对592名6-14岁的中国儿童进行了病例对照研究，包括ADHD（n = 296）和非ADHD（n = 296），年龄和性别匹配。饮食和营养模式，确定使用因素分析和食物频率问卷。采用原子吸收光谱法测定血液必需元素水平。富含贝类、深水鱼、白色肉、淡水鱼、器官肉、真菌和藻类的鱼-白色肉饮食模式与ADHD呈负相关（p = 0.006）。进一步分析发现，富含锌、蛋白质、磷、硒、钙和核黄素的矿物质-蛋白质营养模式与多动症呈负相关（p = 0.014）。此外，血锌也与ADHD呈负相关（p = 0.003）。因此，鱼-白肉膳食模式和矿物质-蛋白质营养模式可能对中国儿童ADHD有有益的影响，血锌可能有助于中国儿童ADHD的鉴别诊断。
Dietary or nutrient patterns represent the combined effects of foods or nutrients, and elucidate efficaciously the impact of diet on diseases. Because the pharmacotherapy on attention deficit hyperactivity disorder (ADHD) was reported be associated with certain side effects, and the etiology of ADHD is multifactorial, this study investigated the association of dietary and nutrient patterns with the risk of ADHD. We conducted a case-control study with 592 Chinese children including ADHD (n = 296) and non-ADHD (n = 296) aged 6–14 years old, matched by age and sex. Dietary and nutrient patterns were identified using factor analysis and a food frequency questionnaire. Blood essential elements levels were measured using atomic absorption spectrometry. A fish-white meat dietary pattern rich in shellfish, deep water fish, white meat, freshwater fish, organ meat and fungi and algae was inversely associated with ADHD (p = 0.006). Further analysis found that a mineral-protein nutrient pattern rich in zinc, protein, phosphorus, selenium, calcium and riboflavin was inversely associated with ADHD (p = 0.014). Additionally, the blood zinc was also negatively related to ADHD (p = 0.003). In conclusion, the fish-white meat dietary pattern and mineral-protein nutrient pattern may have beneficial effects on ADHD in Chinese children, and blood zinc may be helpful in distinguishing ADHD in Chinese children.