POSTEMBRYONIC DEVELOPMENT OF SEROTONIN-LIKE IMMUNOREACTIVITY IN THE CENTRAL NERVOUS-SYSTEM OF THE SNAIL, LYMNAEA-STAGNALIS
POSTEMBRYONIC DEVELOPMENT OF SEROTONIN-LIKE IMMUNOREACTIVITY IN THE CENTRAL NERVOUS-SYSTEM OF THE SNAIL, LYMNAEA-STAGNALIS
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DOI：
10.1002/cne.902800109
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发表时间：
1989-02-01
影响因子：
2.5
通讯作者：
CHIASSON, BJ
中科院分区：
文献类型：
--
作者：
CROLL, RP;CHIASSON, BJ
塘螺（lynaea stagnation）的茅草后生长涉及到组成中枢神经系统的神经节的线性尺寸增加约20倍。为了从细胞的角度解释这种生长，研究了表现出血清素样免疫反应性（slr）的神经元群体的发育变化。研究表明，至少有两个因素有助于神经系统的生长。首先，在接近性成熟的动物中，SLIR细胞的数量从幼体的200-250个增加到大约一倍。细胞数量的增加大部分发生在可识别的离散簇中，以不同的速度和不同的时间添加细胞。slr细胞的数量在弥漫性人群中也有所增加，特别是在成对脚内侧和右侧顶叶神经节。胚胎后未添加已鉴定的细胞。除了神经元数量的增加，淋巴细胞的茅草后发育也涉及到单个细胞的生长。所有检测到的细胞在育后发育过程中都表现出连续的体细胞生长，但不同鉴定的细胞和不同的细胞簇具有不同的相对生长速率。总之，这些结果通过表明神经系统内细胞添加和细胞生长的时间和空间特异性，突出了蜗牛胚胎后发育的复杂性。
Posthatching growth in the pond snail Lymnaea stagnalis involves approximately a 20-fold increase in the linear dimensions of the ganglia composing the central nervous system. Developmental change within the population of neurons exhibiting serotoninlike immunoreactivity (SLIR) was examined in order to explain this growth in cellular terms. The study indicates that at least two factors contribute to the growth of the nervous system. First, SLIR cells approximately double in number from the 200-250 cells in hatchlings to the complement found in animals approaching sexual maturity. Much of this increase in cell number occurred within identifiable discrete clusters adding cells at different rates and at different times. The number of SLIR cells also increased in more diffuse populations, particularly along the medial aspects of the paired pedal and the right parietal ganglion. No identified cells were added postembryonically. In addition to the increases in neuron numbers, posthatching development in Lymnaea also involves the growth of individual cells. All cells examined showed continuous somatic growth during posthatching development, but different identified cells and different cell clusters were characterized by different rates of relative growth. Together, the results highlight the complexity of postembryonic development in the snail by indicating the temporal and spatial specificity for both cell addition and cell growth within the nervous system.