Generation of Bioactive Materials with Rapid Self-Assembling Resorcinarene-Peptides
Generation of Bioactive Materials with Rapid Self-Assembling Resorcinarene-Peptides
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DOI：
10.1002/adma.200802731
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发表时间：
2009-07-07
影响因子：
29.4
通讯作者：
Haycock, John W.
中科院分区：
文献类型：
--
作者：
Charnley, Mirren;Fairfull-Smith, Kathryn;Haycock, John W.
粘合剂间苯二酚芳烃分子在广泛的材料表面上快速自组装。我们已经通过快速“浸渍-干燥”形成方法产生了含有生物活性末端GKP-D-V抗炎肽的间苯二酚芳烃。神经许旺细胞和成纤维细胞在间苯二酚-GKP-D-V层上的生长证明了炎症信号传导的抑制。
Adhesive resorcinarene molecules rapidly self-assemble on a wide range of material surfaces. We have created resorcinarenes that contain a biologically active terminal GKP-D-V anti-inflammatory peptide by a rapid "dip-and-dry" forming method. The growth of neural Schwann and fibroblast cells on a layer of resorcinarene-GKP-D-V demonstrate inhibition of inflammatory signaling.