Google Trends on Human Papillomavirus Vaccine Searches in the United States From 2010 to 2021: Infodemiology Study.
Google Trends on Human Papillomavirus Vaccine Searches in the United States From 2010 to 2021: Infodemiology Study.
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DOI：
10.2196/37656
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发表时间：
2022-08-29
影响因子：
8.5
通讯作者：
Massey, Philip M
中科院分区：
文献类型：
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作者：
Bhagavathula, Akshaya Srikanth;Massey, Philip M
人乳头瘤病毒（HPV）疫苗推荐给青少年和年轻人，以预防HPV相关的癌症和生殖器疣。然而，HPV疫苗在目标年龄组中的接种率并不理想。这项信息学研究的目的是检查2010年1月至2021年12月期间美国与HPV疫苗相关的公共在线搜索。Google Trends（GT）用于探索2010年1月1日至2021年12月31日期间与HPV疫苗相关的在线搜索。使用相对搜索量（RSV）对HPV疫苗的在线搜索和查询进行了调查。进行方差分析，以调查2010年至2021年每年HPV疫苗搜索的季度差异。使用联合点回归确定随时间推移的统计学显著性变化; α水平设定为0.05。与HPV疫苗相关的年度在线搜索量从2010年到2021年有所增加，通常是在与疫苗管理相关的联邦变化之后。Joinpoint回归分析显示，从2010年到2021年，HPV疫苗搜索量平均每年显著增加8.6%（95%CI 5.9%-11.4%）。此外，HPV疫苗的搜索显示出类似的模式，几乎每年8月的搜索兴趣都在增加。在州一级，2010-2021年期间，在加州观察到最高的12年平均RSV（59.9，SD 14.3），在怀俄明州观察到最低（17.4，SD 8.5）。从2010年到2021年，与HPV疫苗相关的在线搜索平均每年增加8.6%，疫苗推荐的关键变化对应了明显的峰值。我们确定了与HPV疫苗相关的在线搜索兴趣的多年模式和州一级的差异。公共卫生组织可以使用GT作为一种工具来描述公共利益，并在美国推广HPV疫苗。
The human papillomavirus (HPV) vaccine is recommended for adolescents and young adults to prevent HPV-related cancers and genital warts. However, HPV vaccine uptake among the target age groups is suboptimal. The aim of this infodemiology study was to examine public online searches in the United States related to the HPV vaccine from January 2010 to December 2021. Google Trends (GT) was used to explore online searches related to the HPV vaccine from January 1, 2010, to December 31, 2021. Online searches and queries on the HPV vaccine were investigated using relative search volumes (RSVs). Analysis of variance was performed to investigate quarterly differences in HPV vaccine searches in each year from 2010 to 2021. A joinpoint regression was used to identify statistically significant changes over time; the α level was set to .05. The year-wise online search volume related to the HPV vaccine increased from 2010 to 2021, often following federal changes related to vaccine administration. Joinpoint regression analysis showed that HPV vaccine searches significantly increased on average by 8.6% (95% CI 5.9%-11.4%) across each year from 2010 to 2021. Moreover, HPV vaccine searches demonstrated a similar pattern across years, with search interest increasing through August nearly every year. At the state level, the highest 12-year mean RSV was observed in California (59.9, SD 14.3) and the lowest was observed in Wyoming (17.4, SD 8.5) during the period of 2010-2021. Online searches related to the HPV vaccine increased by an average of 8.6% across each year from 2010 to 2021, with noticeable spikes corresponding to key changes in vaccine recommendations. We identified patterns across years and differences at the state level in the online search interest related to the HPV vaccine. Public health organizations can use GT as a tool to characterize the public interest in and promote the HPV vaccine in the United States.