Near-infrared spectroscopy measurement of the pulsatile component of cerebral blood flow and volume from arterial oscillations.
Near-infrared spectroscopy measurement of the pulsatile component of cerebral blood flow and volume from arterial oscillations.
复制标题
近红外光谱测量动脉振荡引起的脑血流和体积的脉动成分。
DOI：
10.1117/1.2710250
复制
发表时间：
2007
影响因子：
3.5
通讯作者：
Franceschini,MariaAngela
中科院分区：
文献类型：
--
作者：
Themelis,George;D'Arceuil,Helen;Diamond,SolomonG;Thaker,Sonal;Huppert,TheodoreJ;Boas,DavidA;Franceschini,MariaAngela
We describe a near-infrared spectroscopy (NIRS) method to noninvasively measure relative changes in the pulsate components of cerebral blood flow (pCBF) and volume (pCBV) from the shape of heartbeat oscillations. We present a model that is used and data to show the feasibility of the method. We use a continuous-wave NIRS system to measure the arterial oscillations originating in the brains of piglets. Changes in the animals’ CBF are induced by addingto the breathing gas. To study the influence of scalp on our measurements, comparative, invasive measurements are performed on one side of the head simultaneously with noninvasive measurements on the other side. We also did comparative measurements of CBF using a laser Doppler system to validate the results of our method. The results indicate that for sufficient source-detector separation, the signal contribution of the scalp is minimal and the measurements are representative of the cerebral hemodynamics. Moreover, good correlation between the results of the laser Doppler system and the NIRS system indicate that the presented method is capable of measuring relative changes in CBF. Preliminary results show the potential of this NIRS method to measure pCBF and pCBV relative changes in neonatal pigs.<?xpp l?>
