Changes in X-ray Sensitivity of HeLa Cells during the Division Cycle
Changes in X-ray Sensitivity of HeLa Cells during the Division Cycle
复制标题
HeLa 细胞分裂周期中 X 射线敏感性的变化
作者：
T. Terasima;T. Terasima;L. Tolmach
Puck和Marcus对X射线照射后随机分裂的HeLa S3细胞的繁殖存活率的测量显示，对剂量的指数响应遵循肩部1。然而，不排除这些群体实际上是异质性的可能性，这些细胞在分裂周期中经历了小的或大的但短暂的敏感性波动。我们通过在有丝分裂后的不同时间照射同步增长的种群来检验这种可能性。
MEASUREMENT by Puck and Marcus of the reproductive survival of randomly dividing cultures of HeLa S3 cells after X-irradiation revealed an exponential response to dose following a shoulder1. However, the possibility was not excluded that these populations are in fact heterogeneous, the cells undergoing small, or large but brief, fluctuations in sensitivity during the division cycle. We have examined this possibility by irradiating synchronously growing populations at various times after mitosis.