Novel regression equations of left ventricular dimensions in infants less than 1 year of age and premature neonates obtained from echocardiographic examination
Novel regression equations of left ventricular dimensions in infants less than 1 year of age and premature neonates obtained from echocardiographic examination
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超声心动图检查获得的 1 岁以下婴儿和早产儿左心室尺寸的新回归方程
DOI：
10.1017/s1047951110000661
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发表时间：
2010
影响因子：
1
通讯作者：
H. Nagasawa
中科院分区：
文献类型：
--
作者：
H. Nagasawa
摘要 背景 许多研究报道了通过使用二维超声心动图来估计儿童左心室尺寸的发育，并制定方程来评估正常心脏尺寸。我们报告说，身高是评估儿童左心室正常尺寸最简单、最有用的指标。通过使用体重或体表面积作为指标，发现这些公式估算的“正常”尺寸与 1 岁以下婴儿和新生儿的实际尺寸之间存在差异。我们的目的是以身高为指标，通过二维超声心动图评估1岁以下婴儿和新生儿（包括早产儿）左心室舒张末期内径的正常大小。方法和结果研究组由243名婴儿组成，其中男性123名，女性120名，无先天性心脏病。成熟新生儿和身高小于75厘米的婴儿左心室舒张末期内径（Y）与身高关系的回归方程为Y（毫米）=0.352×身高（厘米）+1.86，早产儿为Y（毫米）=0.495×身高（厘米）−5.43。在婴儿中没有观察到性别的显着差异。结论 先前研究中报告的回归方程不能应用于从婴儿获得的数据。此外，三种不同的公式，以身高为指标，针对每组婴儿，可以有效地应用于实际目的。
Abstract Background Many studies have reported on the estimation of the development of left ventricular dimensions in children by using two-dimensional echocardiography and formulated equations to evaluate normal cardiac dimensions. We reported that height is the most simple and useful index to evaluate the normal dimensions of the left ventricle in children. Disparities have been detected between the “normal” dimensions estimated from these formulae and real dimensions in infants less than 1 year of age and neonates, by using body weight or body surface area as an index. Our objective is to assess the normal size of left ventricular end-diastolic dimension in infants less than 1 year of age and neonates, including premature neonates, by two-dimensional echocardiography by using height as an index. Methods and results The study group consisted of 243 infants, 123 males, and 120 females without congenital cardiac disease. The regression equation for the relationship between left ventricular end-diastolic dimension (Y) and height was Y (millimetre) = 0.352 × height (centimetre) + 1.86 in mature neonates and infants with height of less than 75 centimetres, whereas that in premature neonates was Y (millimetre) = 0.495 × height (centimetre) − 5.43. No significant differences were observed in the infants on the basis of sex. Conclusions The regression equations reported in the previous studies cannot be applied to data obtained from infants. In addition, three different formulae, one for each group of infants by using height as an index can be usefully applied for practical purposes.