Reactivation of medial temporal lobe and occipital lobe during the retrieval of color information: A positron emission tomography study
Reactivation of medial temporal lobe and occipital lobe during the retrieval of color information: A positron emission tomography study
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DOI：
10.1016/j.neuroimage.2006.10.022
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发表时间：
2007-02
期刊：
影响因子：
5.7
通讯作者：
A. Ueno;N. Abe;Maki Suzuki;K. Hirayama;E. Mori;M. Tashiro;M. Itoh;T. Fujii
中科院分区：
文献类型：
--
作者：
A. Ueno;N. Abe;Maki Suzuki;K. Hirayama;E. Mori;M. Tashiro;M. Itoh;T. Fujii
人们普遍认为，事件的记忆痕迹包括关于事件内容和个体经历事件的各种类型的信息。然而，人们对这些不同类型的信息是如何存储和随后提取的知之甚少。一种假设认为，特定事件信息的检索重新激活了在编码该信息期间活跃的区域，并借助于内侧颞叶（MTL）结构的结合功能。我们使用正电子发射断层扫描来识别与颜色信息编码和检索相关的大脑区域。具体来说，我们评估是否重叠活动中发现的MTL结构和颜色相关的皮层区域的编码和检索的颜色信息附加无意义的形状。在研究过程中，受试者被要求编码彩色（红色或绿色）和无色的随机形状。在随后的测试中，受试者只呈现无色的形状，这些形状在编码过程中呈现有或没有颜色，并参与形状和颜色的检索任务。重叠活动被发现在MTL和枕叶（舌和枕下回）在右半球的编码和检索无意义的形状与颜色信息相比，没有颜色信息。虽然有一些局限性要考虑，目前的研究结果似乎支持这样一种观点，即检索特定的事件信息与重新激活的MTL结构和参与编码的信息过程中的区域。
It is widely accepted that memory traces of an event include various types of information about the content of the event and about the circumstances in which the individual experienced it. However, how these various types of information are stored and later retrieved is poorly understood. One hypothesis postulates that the retrieval of specific event information reactivates regions that were active during the encoding of this information, with the aid of binding functions of the medial temporal lobe (MTL) structures. We used positron emission tomography to identify the brain regions related to the encoding and retrieval of color information. Specifically, we assessed whether overlapping activity was found in both the MTL structures and color-related cortical regions during the encoding and retrieval of color information attached with meaningless shapes. During the study, subjects were asked to encode colored (red or green) and achromatic random shapes. At subsequent testing, subjects were presented with only achromatic shapes, which had been presented with or without colors during encoding, and were engaged in retrieval tasks of shapes and colors. Overlapping activity was found in the MTL and occipital lobe (the lingual and inferior occipital gyri) in the right hemisphere during the encoding and retrieval of meaningless shapes with color information compared with those without color information. Although there are some limitations to be considered, the present findings seem to support the view that the retrieval of specific event information is associated with reactivation of both the MTL structures and the regions involved during encoding of the information.