Broader, greener, and more efficient: recent advances in asymmetric transfer hydrogenation.
Broader, greener, and more efficient: recent advances in asymmetric transfer hydrogenation.
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DOI：
10.1002/asia.200800196
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发表时间：
2008-10
期刊：
影响因子：
--
通讯作者：
Chao Wang;Xiaofeng Wu;Jianliang Xiao
中科院分区：
文献类型：
--
作者：
Chao Wang;Xiaofeng Wu;Jianliang Xiao
不对称转移氢化反应在近十年来已成为还原化学中的一种实用工具。这在很大程度上是由Noyori及其同事在20世纪90年代中期的开创性工作引发的，并且是由其对使用H（2）的氢化的补充化学驱动的。这份重点审查报告试图对这一领域的进展提出一个“全面”的概述，重点是过去三年取得的成就。这些包括更有效和“绿色”的金属催化剂，能够氢化以及转移氢化的催化剂，仿生和有机催化剂，以及它们在还原C==O，C==N和C==C键中的应用。还强调了在开发环境友好和可重复使用的催化系统方面的努力。
Asymmetric transfer hydrogenation has become a practically useful tool in reduction chemistry in the last decade or so. This was largely triggered by the seminal work of Noyori and co-workers in the mid-1990s and is driven by its complementing chemistry to hydrogenation employing H(2). This Focus Review attempts to present a "holistic" overview on the advances in the area, focusing on the achievements recorded around the last three years. These include more-efficient and "greener" metal catalysts, catalysts that enable hydrogenation as well as transfer hydrogenation, biomimetic and organocatalysts, and their applications in the reduction of C==O, C==N, and C==C bonds. Also highlighted are efforts in the development of environmentally benign and reusable catalytic systems.