Palladium-catalyzed coupling of azoles or thiazoles with aryl thioethers via C-H/C-S activation.
Palladium-catalyzed coupling of azoles or thiazoles with aryl thioethers via C-H/C-S activation.
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DOI：
10.1021/acs.orglett.5b00510
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发表时间：
2015-02
期刊：
影响因子：
5.2
通讯作者：
Fengxiang Zhu;Zhong‐Xia Wang
中科院分区：
文献类型：
--
作者：
Fengxiang Zhu;Zhong‐Xia Wang
通过芳基硫醚的C（sp（2））-S键活化和唑或噻唑的C-H键活化进行钯催化的交叉偶联。缺电子和富电子的芳基甲基硫醚和二芳基硫醚可以用作偶联配偶体，并且反应耐受一系列官能团，包括MeO、CF 3、CN、PhCO、CONEt 2和Py基团。
Palladium-catalyzed cross-coupling via the C(sp(2))-S bond activation of aryl thioethers and the C-H bond activation of azoles or thiazoles was carried out. Electron-deficient and -rich aryl methyl thioethers and diaryl thioethers can be employed as the coupling partners and the reaction tolerates a range of functional groups including MeO, CF3, CN, PhCO, CONEt2, and Py groups.