Healthcare-associated Staphylococcus aureus bloodstream infection: length of stay, attributable mortality, and additional direct costs
Healthcare-associated Staphylococcus aureus bloodstream infection: length of stay, attributable mortality, and additional direct costs
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DOI：
10.1016/j.bjid.2012.10.001
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发表时间：
2012-12-01
影响因子：
3.4
通讯作者：
Turchi, Marília Dalva
中科院分区：
文献类型：
--
作者：
Primo, Mariusa Gomes Borges;Guilarde, Adriana Oliveira;Turchi, Marília Dalva
本研究旨在确定巴西中部一家教学医院与医疗保健相关的金黄色葡萄球菌血流感染 (BSI) 造成的超额住院时间、额外支出和死亡率。研究设计为匹配（1:1）病例对照。病例定义为年龄 >13 岁、患有与医疗保健相关的金黄色葡萄球菌 BSI 的患者。对照组包括没有金黄色葡萄球菌 BSI 的患者，这些患者在性别、年龄（7 岁）、发病率和基础疾病方面与病例相匹配。数据收集自医疗记录和巴西国家医院信息系统 (Sistema de Informacoes Hospitalares do Sistema Unico de Saude - SIH/SUS)。进行 Wilcoxon 秩和检验来比较病例和对照之间的住院时间和费用。使用麦克尼马尔检验比较了病例和对照之间死亡率的差异。进行 Mantel-Haenzel 分层分析来比较侵入性设备的利用率。使用 Epi Info 6.0 和社会科学统计软件包 (SPSS 13.0) 进行数据分析。对 84 对按性别、年龄、入院时间、发病率和基础疾病进行匹配的病例对照进行了分析。病例和对照的平均住院时间分别为 48.3 天和 16.2 天（p
This study aimed to determine the excess length of stay, extra expenditures, and attributable mortality to healthcare-associated S. aureus bloodstream infection (BSI) at a teaching hospital in central Brazil. The study design was a matched (1:1) case-control. Cases were defined as patients >13 years old, with a healthcare-associated S. aureus BSI. Controls included patients without an S. aureus BSI, who were matched to cases by gender, age ( 7 years), morbidity, and underlying disease. Data were collected from medical records and from the Brazilian National Hospital Information System (Sistema de Informacoes Hospitalares do Sistema Unico de Saude - SIH/SUS). A Wilcoxon rank sum test was performed to compare length of stay and costs between cases and controls. Differences in mortality between cases and controls were compared using McNemar's tests. The Mantel-Haenzel stratified analysis was performed to compare invasive device utilization. Data analyses were conducted using Epi Info 6.0 and Statistical Package for Social Sciences (SPSS 13.0). 84 case-control pairs matched by gender, age, admission period, morbidity, and underlying disease were analyzed. The mean lengths of hospital stay were 48.3 and 16.2 days for cases and controls, respectively (p