Innate immunity in plants: an arms race between pattern recognition receptors in plants and effectors in microbial pathogens.

Innate immunity in plants: an arms race between pattern recognition receptors in plants and effectors in microbial pathogens.
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DOI:
10.1126/science.1171647
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发表时间:
2009-05-08
期刊:
Science (New York, N.Y.)
影响因子:
--
通讯作者:
He SY
He SY
中科院分区:
其他
文献类型:
--
作者:
Boller T;He SY

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多年来,对植物暴露于一般微生物激发子时引发的一系列植物防御反应的研究未得到充分重视,原因很好:没有关键的实验证明它们在病原体感染期间介导植物抗性的重要性。如今,这些微生物诱导子被称为病原体/微生物相关分子模式(PAMP或MAMP),植物反应被称为PAMP触发免疫(PTI)。最近的研究为证明PTI在植物抗病性中的作用的困难提供了一个优雅的解释。事实证明,PTI对抗病性的重要贡献被病原体毒力效应子所掩盖,这些毒力效应子已经进化到抑制PTI。
For many years, research on a suite of plant defense responses initiated when plants are exposed to general microbial elicitors was underappreciated, for a good reason: There has been no critical experimental demonstration of their importance in mediating plant resistance during pathogen infection. Today, these microbial elicitors are named pathogen/microbe - associated molecular patterns (PAMPs or MAMPs) and the plant responses called PAMP - triggered immunity (PTI). Recent studies provide an elegant explanation for the difficulty of demonstrating the role of PTI in plant disease resistance. It turns out that the important contribution of PTI to disease resistance is masked by pathogen virulence effectors that have evolved to suppress it.
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