Comparison of dopamine and noradrenaline release in mouse prefrontal cortex, striatum and hippocampus using microdialysis
Comparison of dopamine and noradrenaline release in mouse prefrontal cortex, striatum and hippocampus using microdialysis
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DOI：
10.1016/s0304-3940(99)00840-x
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发表时间：
1999-12-24
影响因子：
2.5
通讯作者：
Feenstra, MGP
中科院分区：
文献类型：
--
作者：
Ihalainen, JA;Riekkinen, P;Feenstra, MGP
采用体内微透析方法研究了小鼠内侧前额叶皮层、内侧纹状体和海马中多巴胺（DA）和去甲肾上腺素（NA）的体内释放。这些区域NA的基础释放量相似，但纹状体DA比其他区域高13 ~ 30倍。非条件刺激（处理、新奇）诱导纹状体DA显著增加，纹状体除外。纹状体NA对处理的敏感性高于其他区域。1999爱思唯尔科学爱尔兰有限公司版权所有。
In vivo release of dopamine (DA) and noradrenaline (NA) in mouse medial prefrontal cortex, medial striatum and hippocampus was characterized using in vivo microdialysis. Basal release of NA was similar in these areas, but DA in striatum was 13-30 times higher than in other areas. Unconditioned stimuli (handling, novelty) induced strong increases, except for striatal DA. Striatal NA was more sensitive to handling than NA in other areas. (C) 1999 Elsevier Science Ireland Ltd. All rights reserved.