Median sternotomy approach for chronic bovine experiments.
Median sternotomy approach for chronic bovine experiments.
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用于慢性牛实验的正中胸骨切开术方法。
DOI：
10.1097/mat.0b013e31818a30d9
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发表时间：
2008
期刊：
影响因子：
--
通讯作者：
Fukamachi,Kiyotaka
中科院分区：
文献类型：
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作者：
Saeed,Diyar;Zahr,Roula;Shalli,Shanaz;Fumoto,Hideyuki;Horai,Tetsuya;Anzai,Tomohiro;Arakawa,Yoko;Dessoffy,Raymond;Catanese,Jacquelyn;Golding,LeonardAR;Fukamachi,Kiyotaka
侧胸切口是各种心室辅助装置临床前动物试验的传统手术方法。然而，从功能角度来看，正中胸骨切开术被认为是心脏外科手术的最合适入路，尤其是器械植入。本研究的目的是评价在慢性牛研究中进行正中胸骨切开术的结局。进行了3项使用胸骨切开术入路的慢性研究。将手术入路与其他三项动物实验中使用的侧开胸入路进行了比较。还评价了术后恢复速度、疼痛管理、胸骨切开术切口和监测线出口部位愈合和感染。胸骨切开术可更好地进入所有心腔和大血管，并为器械放置提供更多空间。恢复时间与使用侧开胸术入路的恢复时间相似，站立或躺卧时没有观察到额外的困难，也不需要增加疼痛管理。尸检时，胸骨愈合良好，无任何感染迹象。总之，这些研究表明，正中胸骨切开术可成功用于慢性牛研究。这种方法将用于我们未来的双心室辅助装置植入手术。
Lateral thoracotomy is the traditional surgical approach for preclinical animal testing of various ventricular assist devices. Median sternotomy, however, is regarded from a functional standpoint as the most appropriate approach for cardiac surgical procedures, particularly for device implantation. The purpose of this study was to evaluate the outcomes of performing a median sternotomy in chronic bovine studies. Three chronic studies using the sternotomy approach were performed. Surgical access was compared to the lateral thoracotomy approach used in three other animal experiments. Postoperative speed of recovery, pain management, sternotomy incision, and monitoring line exit site healing and infection were also evaluated. With sternotomy, better surgical access to all cardiac chambers and great vessels and more room for device placement were achieved. The recovery time was similar to that using the lateral thoracotomy approach, with no additional difficulties observed in standing or recumbency and no need for increased pain management. At the time of autopsy, the sternum was well healed without any sign of infection. In conclusion, these studies showed that a median sternotomy can be used successfully for chronic bovine studies. This approach will be used for our future biventricular assist device implantation surgeries.