The Development of an Inventory to Assess the Structural Barriers to Clinic Attendance and Pill-taking Amongst Users of Antiretroviral Therapy

The Development of an Inventory to Assess the Structural Barriers to Clinic Attendance and Pill-taking Amongst Users of Antiretroviral Therapy
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DOI:
10.1007/s10461-012-0374-z
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发表时间:
2013-01-01
期刊:
影响因子:
4.4
通讯作者:
Kagee, Ashraf
Kagee, Ashraf
中科院分区:
医学2区
文献类型:
--
作者:
Coetzee, Bronwyne;Kagee, Ashraf

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除了个人和心理因素外,结构性因素也可能降低艾滋病毒感染者最佳坚持抗逆转录病毒治疗(ART)的可能性。在这项混合方法研究中,我们报告了一个量表的开发,用于评估 ART 依从性的各种结构性障碍的显着性。在遵循量表开发的常规指南后,对在南非一家公立医院接受 ART 的 291 名患者进行了两种衡量依从就诊和服药的结构性障碍的量表。探索性因素分析和高阶因素分析均表明,单个潜在一般因素适用于这两种量表。最终量表由就诊结构性障碍量表12个条目和服药结构性障碍量表13个条目组成。两个量表都显示出极好的内部一致性,Cronbach α 系数均高于 0.80。确定量表结构效度的研究可能是这一研究领域的下一步。
In addition to personal and psychological factors, structural factors may reduce the likelihood of optimal adherence to antiretroviral therapy (ART) among persons living with HIV. In this mixed-method study we report on the development of a scale to assess the salience of various structural barriers to ART adherence. After following conventional guidelines for scale development, two scales measuring structural barriers to adherence to clinic attendance and pill-taking were administered to 291 patients receiving ART at a public hospital in South Africa. Both exploratory and higher order factor analysis indicated that a single underlying general factor was appropriate for both scales. The final scales consisted of 12 items for the structural barriers to clinic attendance scale and 13 items for the structural barriers to medication-taking scale. Both scales displayed excellent internal consistency with Cronbach alpha coefficients above 0.80. Research to determine the construct validity of the scales may be a next step in this line of research.