Practical Management of Deep Cutaneous Fungal Infections.

Practical Management of Deep Cutaneous Fungal Infections.
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深部皮肤真菌感染的实用治疗。

DOI:
10.3314/mmj.17.006
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发表时间:
2017
影响因子:
1
通讯作者:
Tomotaka Sato
Tomotaka Sato
中科院分区:
--
文献类型:
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作者:
Tomotaka Sato

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了解深部皮肤真菌感染不仅需要阅读大量的病例报告和检查皮肤病变的典型临床图像,而且还需要对患者进行适当的管理,以防止误诊。在此,我回顾了我最近在日本的8例典型的深部皮肤感染(包括原胞菌病和诺卡氏菌病)的经验。做好KOH直接镜检、皮肤活检、真菌培养、组织病理学标本PAS和Grocott染色镜检这四个处理过程是非常重要的。此外,为了帮助记忆重要疾病的名称,我推荐记忆法“AC PPPS MD”(曲霉病、隐球菌病、暗色丝孢菌病、无绿藻病、假阿列谢病、孢子虫病、足菌病和皮肤癣菌病)。从皮损处培养分离真菌是进行快速、正确诊断的最佳方法。
Understanding deep cutaneous fungal infection requires not only reading many case reports and checking the typical clinical images of skin lesions, but also managing the patients properly to prevent misdiagnosis. Herein, I review my recent experiences with eight typical cases of deep cutaneous infections (including protothecosis and nocardiosis) in Japan. It is very important to do the four management processes; namely, KOH direct microscopic examination, skin biopsy, fungal culture, and microscopic examination of the histopathological specimen of PAS and Grocott staining. Also, to aid in memorizing the names of important diseases, I recommend the mnemonic "AC PPPS MD" (Aspergillosis, Cryptococcosis, Phaeohyphomycosis, Protothecosis, Pseudoallescheriosis, Sporotrichosis, Mycetoma, and Dermatophytosis). Isolation of the fungus by culturing from the skin lesion is the best way to carry out quick and correct diagnosis.