Postnatal development of the monkey's visual system.
Postnatal development of the monkey's visual system.
复制标题
猴子视觉系统的出生后发育。
DOI：
10.1002/9780470720684.ch7
复制
发表时间：
1981
期刊：
影响因子：
--
通讯作者：
F. Vital
中科院分区：
文献类型：
--
作者：
C. Blakemore;F. Vital
出生后神经活动的突然增加可能会影响大脑许多部分的发育。视觉系统提供了一个特别突出的例子，说明出生本身对神经系统成熟的重要意义，因为视觉经验显然不可能在子宫内获得。传入神经元的活动在维持甚至引导视觉通路中功能连接的形成方面的作用，已经在许多物种中得到了广泛的研究：在灵长类动物中的这项工作可能会让我们深入了解人类的相同过程，以及某些视觉发育障碍的病因。我们对猴的外侧膝状体核（LGN）和初级视觉皮层进行了解剖学和生理学实验，外侧膝状体核（LGN）接受来自视神经的输入，初级视觉皮层向LGN发送轴突。在这两个结构中，出生后都有巨大的功能变化，但LGN中的结构似乎不依赖于正常的视觉刺激，而皮层中的结构似乎主要依赖于视觉输入。
The sudden increase of nervous activity after birth may influence the development of many parts of the brain. The visual system provides a particularly striking example of the crucial significance of birth itself in the maturation of the nervous system, for visual experience is obviously unlikely in utero. The role of the activity of afferent neurons in maintaining, even guiding, the formation of functional connections in the visual pathways has been extensively studied in a variety of species: such work in primates might give insight into the same process in man and into the aetiology of certain developmental disorders of vision. We have performed anatomical and physiological experiments on the monkey's lateral geniculate nucleus (LGN), which receives input from the optic nerves, and the primary visual cortex, to which the LGN sends its axons. In both structures there are enormous functional changes after birth, but those in the LGN seem not to depend on normal visual stimulation while those in the cortex seem crucially dependent on visual input.