Blockade of synaptic inhibition reveals long-lasting synaptic excitation in isolated turtle olfactory bulb.
Blockade of synaptic inhibition reveals long-lasting synaptic excitation in isolated turtle olfactory bulb.
复制标题
突触抑制的阻断揭示了离体龟嗅球中持久的突触兴奋。
DOI：
10.1152/jn.1981.46.3.649
复制
发表时间：
1981
影响因子：
2.5
通讯作者：
Shepherd,GM
中科院分区：
文献类型：
--
作者：
Nowycky,MC;Mori,K;Shepherd,GM
6.根据本文和前一篇文章中的证据，可以得出结论，I，和I2是GABA能，Cl-介导的反应颗粒细胞和二尖瓣细胞之间的树-树突触产生的。抑制电位的消除揭示了一个新的，持久的去极化，这是只产生的顺向刺激。可能的网站和机制的E，产生内或附近的嗅球和这种类型的兴奋作用的功能意义的突触电路进行了讨论。
6. Based on evidence in this and the preceding paper, it is concluded that I, and I2 are GABAergic, Cl-mediated responses produced by dendrodendritic synapses between granule cells and mitral cells. Elimination of the inhibitory potentials reveals a new, long-lasting depolarization, which is produced only by orthodromic stimulation. Possible sites and mechanisms of E, generation by synaptic circuits within or near the olfactory glomerulus and the functional significance of this type of excitatory action are discussed.