Improving the Capacity of Molecular Communication Using Enzymatic Reaction Cycles
Improving the Capacity of Molecular Communication Using Enzymatic Reaction Cycles
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DOI：
10.1109/tnb.2017.2753230
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发表时间：
2017-12-01
影响因子：
3.9
通讯作者：
Chou, Chun Tung
中科院分区：
文献类型：
--
作者：
Awan, Hamdan;Chou, Chun Tung
本文考虑了基于扩散的分子通信链路的容量，假设接收器使用化学反应。关键的贡献是我们表明，酶促反应循环，这是一类常见的化学反应，在细胞中包括一个向前和向后的酶促反应，可以提高通信链路的容量。分析酶促反应循环的技术难点在于其反应速率是非线性的。我们通过假设酶促反应循环中某些化学物质的量很大来处理这个问题。为了进一步简化问题，我们使用奇异摄动来研究一个特定的操作制度的酶促反应循环。这使我们能够推导出通道增益的封闭形式表达式。该表达式表明，我们可以通过增加酶促反应循环中底物的总量来提高通道增益。通过数值计算，我们表明，酶促反应周期的效果是增加信道增益，降低噪声，从而导致更好的信噪比，进而提高通信容量。此外，我们表明，我们可以通过增加酶促反应循环中底物的总量来增加容量。
This paper considers the capacity of a diffusion-based molecular communication link assuming the receiver uses chemical reactions. The key contribution is we show that enzymatic reaction cycles, which is a class of chemical reactions commonly found in cells consisting of a forward and a backward enzymatic reaction, can improve the capacity of the communication link. The technical difficulty in analyzing enzymatic reaction cycles is that their reaction rates are nonlinear. We deal with this by assuming that the amount of certain chemicals in the enzymatic reaction cycle is large. In order to simplify the problem further, we use singular perturbation to study a particular operating regime of the enzymatic reaction cycles. This allows us to derive a closed-form expression of the channel gain. This expression suggests that we can improve the channel gain by increasing the total amount of substrate in the enzymatic reaction cycle. By using numerical calculations, we show that the effect of the enzymatic reaction cycle is to increase the channel gain and to reduce the noise, which results in a better signal-to-noise ratio and in turn a higher communication capacity. Furthermore, we show that we can increase the capacity by increasing the total amount of substrate in the enzymatic reaction cycle.