The neural correlates of impaired inhibitory control in anxiety
The neural correlates of impaired inhibitory control in anxiety
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DOI：
10.1016/j.neuropsychologia.2011.01.019
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发表时间：
2011-04-01
期刊：
影响因子：
2.6
通讯作者：
Derakshan, Nazanin
中科院分区：
文献类型：
--
作者：
Ansari, Tahereh L.;Derakshan, Nazanin
根据注意力控制理论（Eysenck et al.，2007）焦虑通过增加刺激驱动过程对有效的自上而下控制的影响来损害工作记忆的抑制功能。我们研究了神经相关的抑制控制受损的焦虑使用antisaccade任务。低焦虑和高焦虑的参与者进行反和正视任务和电生理活动的记录。与先前的研究一致，高焦虑个体与低焦虑个体相比，在对被抑制目标的反应中有更长的反跳潜伏期。我们的预测的中心，高焦虑的人表现出较低的ERP活动，在额中央和中央记录网站，比低焦虑的人，在发病前的一段时间内，要被抑制的目标正确的antisaccade试验。我们的研究结果表明，焦虑干扰了有效的招聘自上而下的机制所需的抑制优势反应。讨论了当前焦虑注意力控制模型的含义（Bishop，2009：Eysenck等人，2007年）。(C)2011爱思唯尔有限公司保留所有权利。
According to Attentional Control Theory (Eysenck et al., 2007) anxiety impairs the inhibition function of working memory by increasing the influence of stimulus-driven processes over efficient top-down control. We investigated the neural correlates of impaired inhibitory control in anxiety using an antisaccade task. Low- and high-anxious participants performed anti- and prosaccade tasks and electrophysiological activity was recorded. Consistent with previous research high-anxious individuals had longer antisaccade latencies in response to the to-be-inhibited target, compared with low-anxious individuals. Central to our predictions, high-anxious individuals showed lower ERP activity, at frontocentral and central recording sites, than low anxious individuals, in the period immediately prior to onset of the to-be-inhibited target on correct antisaccade trials. Our findings indicate that anxiety interferes with the efficient recruitment of top-down mechanisms required for the suppression of prepotent responses. Implications are discussed within current models of attentional control in anxiety (Bishop, 2009: Eysenck et al., 2007). (C) 2011 Elsevier Ltd. All rights reserved.