STUDY OF BARRELS AND PYRAMIDAL DENDRITIC CLUSTERS IN CEREBRAL-CORTEX
STUDY OF BARRELS AND PYRAMIDAL DENDRITIC CLUSTERS IN CEREBRAL-CORTEX
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DOI：
10.1016/0006-8993(74)90804-x
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发表时间：
1974-01-01
期刊：
影响因子：
2.9
通讯作者：
PETERS, A
中科院分区：
文献类型：
--
作者：
FELDMAN, ML;PETERS, A
在光学显微镜下检查了大鼠、猫、猕猴和人新皮质几个区域的切向切片。两种类型的神经元组织-桶和树突簇-进行了描述。在大鼠顶叶皮层第IV层观察到桶形的星状细胞胞体聚集。这些桶的轴垂直于软膜表面，并且很明显，因为它们的壁中神经元的浓度是桶空腔中神经元的1.5-2.0倍。虽然在其他物种的皮质中观察到一些环形的神经元聚集体，但它们不能被一致地发现。大鼠和猫的树突簇由锥体细胞胞体垂直放射状排列的顶树突群组成。它们的形式因皮层区域和物种而异。有人提出，集群是哺乳动物新皮层的一个普遍特征。没有明显的空间关系之间存在桶和集群的大鼠顶叶皮层。树突簇的尺寸太小，无法将单个簇等同于神经生理学定义的列。桶，在那些地区和物种中，他们已经被描述，更有可能的候选人，虽然他们非常有限的分布表明，对于大多数功能柱，其他形态相关存在。这表明，在一般情况下，形态要素swhich主要占柱不是perikaryal聚集体，但外部和内部轴突终末的模式。
Tangential sections from several areas of rat, cat, macaque, and human neocortex were examined in the light microscope. Two types of neuronal organization — barrels and dendritic clusters — are described. Barrel-shaped aggregations of stellate cell perikarya were examined in layer IV of the rat parietal cortex. The barrels have their axes oriented perpendicular to the pial surface and are apparent because the concentration of neurons in their walls is 1.5–2.0 times that in the barrel hollows. Although some ring-shaped neuronal aggregates were observed in the cortices in other species, they could not be found consistently. The dendritic clusters, in rat and cat, consist of groups of apical dendrites which radiate vertically from pyramidal cell perikarya. Their form varies with both cortical region and species. It is proposed that clusters are a general feature of mammalian neocortex. No readily apparent spatial relationship exists between barrels and clusters of the rat parietal cortex. The dimensions of the dendritic clusters are too small to equate individual clusters with neurophysiologically defined columns. The barrels, in those regions and species in which they have been described, are more likely candidates, although their very limited distribution suggests that, for most functional columns, other morphological correlates exist. It is suggested that, in general, the morphological element swhich primarily account for the columns are not perikaryal aggregates but patterns of extrinsic and intrinsic axon terminals.