LIPASE CATALYZED FORMATION OF FATTY AMIDES
LIPASE CATALYZED FORMATION OF FATTY AMIDES
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DOI：
10.1007/bf02662325
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发表时间：
1991-02-01
影响因子：
2
通讯作者：
FEAIRHELLER, SH
中科院分区：
文献类型：
--
作者：
BISTLINE, RG;BILYK, A;FEAIRHELLER, SH
发现某些脂肪酶制剂有助于在20 ℃己烷中制备脂肪酰胺。 研究的脂肪酶制剂来自真菌Candida rugosa、Rhizomucor miehei和猪胰腺。 反应物是各种伯烷基胺和脂肪酸甲酯或甘油三酯。 用R.固定在固体载体上作为催化剂的Miehei脂肪酶制剂，尽管所有三种脂肪酶制剂在这些条件下都显示出一定的催化活性，此外，还显示出对脂肪酸和烷基胺链长的不同种类的选择性。 在使用一种脂肪酸作为底物或一种仲胺的类似实验中没有观察到反应。
Certain lipase preparations were found to facilitate the preparation of fatty amides at 20-degrees-C in hexane. Lipase preparations investigated were from the fungi Candida rugosa, Rhizomucor miehei and porcine pancreas. Reactants were various primary alkylamines and fatty acid methyl esters or triglycerides. Moderate yields of fatty amides were obtained using a R. miehei lipase preparation which is immobilized on a solid support as catalyst, although all three lipase preparations showed some catalytic activity under these conditions and, in addition, showed different kinds of selectivity for fatty acid and alkylamine chain lengths. No reaction was observed in similar experiments using one fatty acid as the substrate or one secondary amine.