Evidence for an intrinsic binding force between dodecaborate dianions and receptors with hydrophobic binding pockets.
Evidence for an intrinsic binding force between dodecaborate dianions and receptors with hydrophobic binding pockets.
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DOI：
10.1039/c6cc01233g
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发表时间：
2016-04
影响因子：
4.9
通讯作者：
J. Warneke;Carsten Jenne;J. Bernarding;V. Azov;M. Plaumann
中科院分区：
文献类型：
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作者：
J. Warneke;Carsten Jenne;J. Bernarding;V. Azov;M. Plaumann
气相结合研究表明，双阴离子卤代闭合十二硼酸盐[B12X12](2-)与几种中性有机受体之间存在着强烈的内在分子间相互作用。四硫富瓦烯主体的氧化允许在超分子络合物中的两种主-客体结合模式之间切换。β-环糊精与[B12F12](2-)的络合物在气相中表现出显著的稳定性，并成功地作为载体将硼簇输送到癌细胞中。
A gas phase binding study revealed strong intrinsic intermolecular interactions between dianionic halogenated closo-dodecaborates [B12X12](2-) and several neutral organic receptors. Oxidation of a tetrathiafulvalene host allowed switching between two host-guest binding modes in a supramolecular complex. Complexes of β-cyclodextrin with [B12F12](2-) show remarkable stability in the gas phase and were successfully tested as carriers for the delivery of boron clusters into cancer cells.