Heart failure with preserved ejection fraction.

Heart failure with preserved ejection fraction.
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DOI:
10.1007/978-1-84882-185-9_5
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发表时间:
2006-10
期刊:
The New England journal of medicine
影响因子:
--
通讯作者:
A. Ahmed;J. Fleg;M. Gheorghiade
A. Ahmed;J. Fleg;M. Gheorghiade
中科院分区:
其他
文献类型:
--
作者:
A. Ahmed;J. Fleg;M. Gheorghiade

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2007年,据估计,美国将在心力衰竭的直接和间接成本上花费332亿美元。2004年,医院因心力衰竭出院的人数从25年前的399,000人增加到1,099,000人。2002年,心力衰竭的总死亡人数为296,700人。1心衰患者的射血分数(HFPEF)保留的比例随着时间的推移而增加,与收缩功能降低的患者不同,存活率并没有明显的改善。此外,尽管患病率不断上升,但设计良好的大型临床试验寥寥无几。3、4本章的目的是在保留射血分数的情况下定义心力衰竭,报告目前对病因的理解,确定评估这种形式的心力衰竭的方法,并讨论当前的治疗策略。
In 2007, it was estimated that the United States would spend $33.2 billion dollars on both the direct and indirect costs of heart failure (HF). In 2004, hospital discharges for HF numbered 1,099,000 up from 399,000, twenty-five years prior. In 2002, total-mention mortality for HF was 296,700 people. 1 The proportion of patients with heart failure with preserved ejection fraction (HFPEF) is increasing over time, and unlike those with reduced systolic function, survival is not appreciably improving. 2 In addition, despite the growing prevalence, few well-designed, large clinical trials exist. 3, 4 This chapter is intended to define heart failure in the setting of preserved ejection fraction, report the current understanding of causation, identify methods to assess this form of heart failure, and discuss current strategies for treatment.