Evaluation of exercised or cooled skeletal muscle on the basis of diffusion-weighted magnetic resonance imaging
Evaluation of exercised or cooled skeletal muscle on the basis of diffusion-weighted magnetic resonance imaging
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DOI：
10.1007/s00421-008-0954-9
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发表时间：
2009-02
影响因子：
3
通讯作者：
O. Yanagisawa;D. Shimao;K. Maruyama;Matthew Nielsen
中科院分区：
文献类型：
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作者：
O. Yanagisawa;D. Shimao;K. Maruyama;Matthew Nielsen
在这项研究中，我们根据磁共振(MR)弥散加权图像(DWI)的表观扩散系数(ADC)值来评估锻炼或降温骨骼肌后的生理变化。分别于运动前、运动后(22例)或降温后(19例)用1.5T磁共振成像仪测量踝背屈肌的弥散系数。这项练习包括步行5分钟，脚踝背屈，以及脚踝背屈30次。对踝背屈肌进行0°C降温30min。ADC值被计算为ADC1-反映扩散和灌流，ADC2-近似于运动前和运动后或降温后踝背屈肌的真实扩散系数。ADC1和ADC2随运动增加而显著增加，随降温时间延长而降低(P<；P<；0.05)。同时考虑扩散和灌流，ADC值使我们能够根据水分子和微循环的运动来评估运动或降温引起的肌肉内变化。
In this study, we assessed the physiological changes after exercising or cooling skeletal muscles on the basis of the apparent diffusion coefficient (ADC) values in magnetic resonance (MR) diffusion-weighted images (DWIs). DWIs of the ankle dorsiflexors were acquired with a 1.5-T MR device before and after exercising (22 subjects) or cooling (19 subjects). The exercise comprised a 5-min walk with the ankles dorsiflexed and a 30-time ankle dorsiflexion. Cooling (0°C) of the ankle dorsiflexors was performed for 30 min. ADC values were calculated as ADC1—reflecting diffusion and perfusion and ADC2—approximating the true diffusion coefficient of the ankle dorsiflexors before and after exercising or cooling. ADC1 and ADC2 significantly increased with exercise and decreased with cooling (P< 0.05). Considering both diffusion and perfusion, ADC values allowed us to evaluate the intramuscular changes induced by exercising or cooling in terms of the motion of water molecules and microcirculation.