Sufficient Cause Representation of the Four-way Decomposition for Mediation and Interaction.
Sufficient Cause Representation of the Four-way Decomposition for Mediation and Interaction.
复制标题
中介和相互作用四向分解的充分原因表示。
DOI:
10.1097/ede.0000000000000521
复制
发表时间:
2016
期刊:
影响因子:
--
通讯作者:
Shrier,Ian
中科院分区:
文献类型:
--
作者:
VanderWeele,TylerJ;Shrier,Ian
Recent work1 has shown how a total effect of an exposure on an outcome, in the context of a mediator with which the exposure might interact, could be decomposed into four components: that due to just mediation, that due to just interaction, that due to both mediation and interaction, and that due to neither mediation nor interaction. In this research letter, we show how each of these four components can be expressed within the sufficient cause framework allowing for mediation. 2, 3 Let A be an exposure, M a mediator, and Y an outcome. For simplicity, we consider the case in which A, M, and Y are all binary. Within the counterfactual framework, we define Ya as the outcome Y we would have observed if A had been set to a. the total effect is defined by Y1–Y0. We define Yam as the potential outcome Y if A were set to a, and M were set to m. We define Ma as the potential outcome M if A were set to a. We make consistency assumptions that Ya= Y and
影响因子:
5
作者:
VanderWeele, Tyler J.;Robins, James M.
通讯作者:
Robins, James M.