Spatio-temporal current density reconstruction (stCDR) from EEG/MEG-data

Spatio-temporal current density reconstruction (stCDR) from EEG/MEG-data
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DOI:
10.1023/a:1007855119092
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发表时间:
2001-03-01
期刊:
影响因子:
2.7
通讯作者:
Buchner, H
Buchner, H
中科院分区:
医学3区
文献类型:
--
作者:
Darvas, F;Schmitt, U;Buchner, H

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Among the different approaches to the bioelectromagnetic inverse problem, the current-density reconstruction methods (CDR) provide the most general solutions. Since the inverse problem does not have a unique solution, model assumptions have to be taken into account. Multi-channel measurements contain not only spatial, but also temporal information about the sources, so a naturally extension to existing methods leads to spatio-temporal model constraints. Spatio-temporal CDR's (stCDR) have been tested in simplified volume conductor models, assuming different spatial model constraints and a smooth temporal activation model. Comparison to existing spatial model constraints showed a significant improvement of spatial and temporal resolution of the reconstructed sources for the spatio-temporal models especial in noisy data.