Taenia multiceps coenurosis in Tanzania: a major and under-recognised livestock disease problem in pastoral communities
Taenia multiceps coenurosis in Tanzania: a major and under-recognised livestock disease problem in pastoral communities
复制标题
DOI：
10.1136/vr.105186
复制
发表时间：
2019-02-01
影响因子：
2.2
通讯作者：
Allan, Kathryn J.
中科院分区：
文献类型：
--
作者：
Hughes, Ellen C.;Kibona, Tito K.;Allan, Kathryn J.
据报道，坦桑尼亚牧民中出现了一种小型反刍动物神经系统综合征，当地称为“ormilo”。本研究在四个受影响的牧区进行，以确定患病率和相关的危险因素，观察临床体征并调查综合征的病因。在四个研究村庄的所有家庭（n=480）进行问卷调查。总体而言，94%的家庭在过去12个月内报告至少一例病例。按村庄划分，12个月期间个人一级的流行率从11%到34%不等，相当于四个村庄约10 000只小反刍动物。随机抽取了38户进行进一步调查。本体感觉缺陷和无力是受累动物中最常见的临床体征。在选择进行尸检的39只受影响动物中，有32只（82%）检测到与多头带绦虫感染一致的脑和脊髓囊肿。给狗喂食小反刍动物的大脑被认为是该综合征的一个重要风险因素，即使在没有养狗的家庭中也是如此。这项研究证实了脑多头蚴病是坦桑尼亚北方小型反刍动物神经系统疾病的主要原因，并强调迫切需要进一步调查，以量化疾病负担，并确定和实施控制措施。
A neurological syndrome of small ruminants, known locally as 'ormilo', has been reported among pastoralist livestock keepers in Tanzania. This study was carried out in four affected pastoral communities to determine the prevalence and associated risk factors, characterise the clinical signs and investigate the aetiology of the syndrome. Questionnaires were administered at all households (n=480) within four study villages. Overall, 94 per cent of households reported at least one case in the previous 12 months. By village, the individual-level 12-month period prevalence ranged from 11 per cent to 34 per cent, equivalent to about 10,000 small ruminants across the four villages. Thirty-eight households were randomly selected for further investigation. Proprioceptive deficits and weakness were the most commonly observed clinical signs in affected animals. Brain and spinal cord cysts consistent with Taenia multiceps infection were detected in 32 (82 per cent) of 39 affected animals selected for postmortem examination. Feeding small ruminant brains to dogs was identified as an important risk factor for the syndrome, even in households that did not own dogs. This study confirms cerebral coenurosis as a major cause of small ruminant neurological disease in northern Tanzania and highlights the urgent need for further investigation to quantify the disease burden and to identify and implement control measures.