Feasibility study of 3-T MR imaging of the skin
Feasibility study of 3-T MR imaging of the skin
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DOI：
10.1007/s00330-009-1348-z
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发表时间：
2009-07-01
影响因子：
5.9
通讯作者：
Kastler, Bruno
中科院分区：
文献类型：
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作者：
Aubry, Sebastien;Casile, Celine;Kastler, Bruno
本研究的目的是评估皮肤 3-T 磁共振 (MR) 成像的质量，描述 3T 皮肤解剖结构并讨论皮肤 MRI 的未来前景。为我们的 3-T MRI 系统开发了 7 厘米单元件表面接收器线圈。通过三维 FIESTA 采集序列和自旋回波 T1 加权序列 (SET1) 获得薄片。前瞻性分析由两名放射科医生独立进行两次。 36 名健康志愿者被纳入其中，并接受了面部和小腿的 MRI 检查。根据皮肤层的可见性和伪影的量化来评估图像质量。高场强 MR 能够以高空间面内分辨率 (87-180 A mu m) 对皮肤进行成像，整个检查持续 15-20 分钟。小牛的图像质量非常好（平均 SET1 质量 = 96%），具有较高的观察者内和观察者间相关性（涉及表皮、真皮和皮下组织可见度的 SET1 kappa 系数为千分之 0.84）。运动伪影导致面部质量和再现性略有下降。总之，3-T MR 可以对皮肤进行高空间分辨率成像，并有可能提供一种准确的非侵入性皮肤分析方法。
The purpose of this study was to assess the quality of 3-T magnetic resonance (MR) imaging of the skin, to describe skin anatomy at 3 T and to discuss future prospects of skin MRI. A 7-cm single-element surface receiver coil was developed for our 3-T MRI system. Thin sections were obtained with a three-dimensional FIESTA acquisition sequence and a spin-echo T1-weighted sequence (SET1). Prospective analysis was performed twice by two radiologists independently. Thirty-six healthy volunteers were included and underwent MRI on the face and the calf. Image quality was assessed regarding visibility of skin layers and quantification of artefacts. High field strength MR enables imaging of the skin with a high spatial in-plane resolution (87-180 A mu m), the total examination lasting 15-20 min. Image quality was excellent for the calf (mean SET1 quality = 96%) with a high intra- and interobserver correlation (SET1 kappa coefficient concerning visibility of epidermis, dermis and hypodermis a parts per thousand yen 0.84). Motion artefacts resulted in a small loss of quality and reproducibility for the face. In conclusion, 3-T MR allows high spatial resolution imaging of the skin and can potentially provide an accurate noninvasive means of analysing the skin.