Did the fat lady sing?
Did the fat lady sing?
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那个胖女人唱歌吗？
DOI：
10.1097/01.ccm.0000202444.39802.b0
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发表时间：
2006
影响因子：
8.8
通讯作者：
Taegtmeyer,Heinrich
中科院分区：
文献类型：
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作者：
Taegtmeyer,Heinrich
没有人知道“直到胖女人唱歌才结束”这句陈词滥调的起源，尽管这句话是对当前关于超重或肥胖对一个人的健康是好是坏的争论的公平描述。在过去的20年里，肥胖和2型糖尿病的患病率在美国已经上升到前所未有的水平，肥胖仅次于烟草相关疾病，成为可预防死亡的第二大原因（1）。肥胖是代谢综合征作为心血管疾病风险因素的基石（2），也与某些形式的癌症有关。来自Frachial研究的数据已经确定肥胖是心力衰竭发展的独立风险因素（3）。除此之外，还有许多合并症，从退行性关节疾病到睡眠呼吸暂停，结论很简单：肥胖不利于健康。
Nobody knows the origin of the cliché “It’s not over till the fat lady sings,” although these words are a fair description of the current debate about whether being overweight or obese is good or bad for a person’s health. The arguments run as follows.During the past 2 decades the prevalence of obesity and type 2 diabetes has increased to unprecedented levels in the United States, placing obesity right after tobacco-related diseases as the number two cause of preventable death (1). Obesity is the cornerstone for the metabolic syndrome as a risk factor for cardiovascular disease (2) and is also associated with certain forms of cancer. Data from the Framingham study have identified obesity as an independent risk factor for the development of heart failure (3). Add to this a host of comorbidities, ranging from degenerative joint disease to sleep apnea, and the conclusion is simple: obesity is bad for one’s health.